Journal ArticleDOI
A review of fiber-optic biosensors
TLDR
Tapered fiber-optic biosensors (TFOBS) as mentioned in this paper are a type of FOBS which rely on special geometries to expose the evanescent field to interact with samples.Abstract:
Fiber-optic biosensors (FOBS) are optical fiber-derived devices which use optical field to measure biological species such as cells, proteins, and DNA. Because of their efficiency, accuracy, low cost, and convenience, FOBS are promising alternatives to traditional immunological methods for biomolecule measurements. Tapered fiber-optic biosensors (TFOBS) are a type of FOBS which rely on special geometries to expose the evanescent field to interact with samples. In order to amplify sensitivity and selectivity, TFOBS are often used with various optical transduction mechanisms such as changes in refractive index, absorption, fluorescence, and Surface Plasmon Resonance. In this review, the basic principles of TFOBS are summarized. Various common geometries for evanescent sensing and the influence of geometric parameters on optical principles are reviewed. Finally, a detailed account of the studies done to date for biomolecules detection using TFOBS will be provided. © 2007 Elsevier B.V. All rights reserved.read more
Citations
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Journal ArticleDOI
A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors.
V. Naresh,Nohyun Lee +1 more
TL;DR: A biosensor is an integrated receptor-transducer device, which can convert a biological response into an electrical signal as mentioned in this paper, which can transform biological signals into electrochemical, electrical, optical, gravimetric, or acoustic signals.
Journal ArticleDOI
Advances in biosensors: Principle, architecture and applications ☆
Veeradasan Perumal,Uda Hashim +1 more
TL;DR: The goal of this combination is to utilize the high sensitivity and selectivity of biological sensing for analytical purposes in various fields of research and technology.
Journal ArticleDOI
Disposable nucleic acid biosensors based on gold nanoparticle probes and lateral flow strip.
TL;DR: The new nucleic acid biosensor provides a rapid, sensitive, low cost, and quantitative tool for the detection of nucleic acids samples and shows great promise for in-field and point-of-care diagnosis of genetic diseases and detection of infectious agents or warning against biowarfare agents.
Fundamentals of optical fibers
TL;DR: In this article, the authors present an analysis of the weakly-guiding fibers with step index profiles and their effect on wave propagation in the context of sourceless media, and the results show that these properties can be used to predict the wave propagation properties.
Journal ArticleDOI
Novel U-bent fiber optic probe for localized surface plasmon resonance based biosensor.
TL;DR: A sensor for sensitive measurement of refractive index (RI) with the help of optical absorbance properties of gold nanoparticles (GNP) coupled to an efficient optical transducer in the form of a U-bent fiber optic probe is described.
References
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Book
Optical Fiber Communications
TL;DR: The concept of WDM combined with optical amplifiers has resulted in communication links that allow rapid communications between users in countries all over the world as discussed by the authors, which is known as wavelength division multiplexing (WDM).
Journal ArticleDOI
Biosensors in clinical chemistry.
TL;DR: The future will include biosensors based on synthetic recognition elements to allow broad applicability to different classes of analytes and modes of transduction extending lower limits of sensitivity.
Fundamentals of optical fibers
TL;DR: In this article, the authors present an analysis of the weakly-guiding fibers with step index profiles and their effect on wave propagation in the context of sourceless media, and the results show that these properties can be used to predict the wave propagation properties.
Journal ArticleDOI
Highly sensitive differential phase-sensitive surface plasmon resonance biosensor based on the Mach–Zehnder configuration
TL;DR: A high-sensitivity surface plasmon resonance (SPR) biosensor based on the Mach-Zehnder interferometer design is presented and a significant improvement over previously obtained results should allow SPR biosensors to become a possible replacement for conventional biosensing techniques based on fluorescence.
Journal ArticleDOI
A fiber-optic evanescent wave DNA biosensor based on novel molecular beacons.
Xiaojing Liu,Weihong Tan +1 more
TL;DR: The result shows divalent cations play a more important role than monovalent cations in stabilizing the MB stem hybrids and in accelerating the hybridization reaction with target DNA/RNA molecules.