A Review of the Effectiveness of Neuroimaging Modalities for the Detection of Traumatic Brain Injury
Franck Amyot,David B. Arciniegas,Brazaitis Mp,Curley Kc,Ramon Diaz-Arrastia,Amir H. Gandjbakhche,Herscovitch P,Hinds Sr nd,Geoffrey T. Manley,Anthony Pacifico,Razumovsky A,Jason D. Riley,Salzer W,Shih R,James G. Smirniotopoulos,Stocker D +15 more
TLDR
Although CT, MRI, and TCD were determined to be the most useful modalities in the clinical setting, no single imaging modality proved sufficient for all patients due to the heterogeneity of TBI; all imaging modalities reviewed demonstrated the potential to emerge as part of future clinical care.Abstract:
The incidence of traumatic brain injury (TBI) in the United States was 3.5 million cases in 2009, according to the Centers for Disease Control and Prevention. It is a contributing factor in 30.5% of injury-related deaths among civilians. Additionally, since 2000, more than 260,000 service members were diagnosed with TBI, with the vast majority classified as mild or concussive (76%). The objective assessment of TBI via imaging is a critical research gap, both in the military and civilian communities. In 2011, the Department of Defense (DoD) prepared a congressional report summarizing the effectiveness of seven neuroimaging modalities (computed tomography [CT], magnetic resonance imaging [MRI], transcranial Doppler [TCD], positron emission tomography, single photon emission computed tomography, electrophysiologic techniques [magnetoencephalography and electroencephalography], and functional near-infrared spectroscopy) to assess the spectrum of TBI from concussion to coma. For this report, neuroimag...read more
Citations
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Journal ArticleDOI
Neurovascular hypoxia after mild traumatic brain injury in juvenile mice correlates with heart–brain dysfunctions in adulthood
Katherine Leyba,Nitchawat Paiyabhroma,John P Salvas,Frederick W. Damen,Alicia Janvier,Emma Zub,Corinne Bernis,Richard Rouland,Christophe J. Dubois,Jérôme Badaut,Sylvain-Luc Richard,Nicola Marchi,Craig J. Goergen,Pierre Sicard +13 more
TL;DR: In this paper , the exact functional and temporal dynamics and the associations between heart and brain pathophysiological trajectories are not understood, and the authors suggest that mild traumatic brain injury (mTBI) in pediatric patients may lead to an increased risk of cardiac events.
DissertationDOI
Recovery-related brain alterations after mild traumatic brain injury: a longitudinal, multimodal imaging approach
TL;DR: The results show that mTBI-induced neuroplasticity differs in time course between brain regions, with highly interconnected hubs being the slowest to recover.
Book ChapterDOI
Neuroimaging Biomarkers for the Neuropsychological Investigation of Concussive Brain Injury (CBI) Outcome
Erin D. Bigler,Jeff Victoroff +1 more
Journal ArticleDOI
Temporary or Permanent? A Clinical Challenge in the Evaluation of Traumatic Brain Injury Patients with Unconsciousness and Normal Initial Head CT
Cheng-Yu Li,Chi-Cheng Chuang,Ching-Chang Chen,Po-Hsun Tu,Ting-An Hsu,Yu-Chi Kuo,Chien-Hung Liao,Chi Hsun Hsieh,Chih-Yuan Fu +8 more
TL;DR: For TBI patients with unconsciousness and normal initial head CT, a higher probability of regaining consciousness was observed in those who underwent early airway protection and who improved 2 points in 72-h GCS score.
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