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Open AccessJournal ArticleDOI

A Review of the Effectiveness of Neuroimaging Modalities for the Detection of Traumatic Brain Injury

TLDR
Although CT, MRI, and TCD were determined to be the most useful modalities in the clinical setting, no single imaging modality proved sufficient for all patients due to the heterogeneity of TBI; all imaging modalities reviewed demonstrated the potential to emerge as part of future clinical care.
Abstract
The incidence of traumatic brain injury (TBI) in the United States was 3.5 million cases in 2009, according to the Centers for Disease Control and Prevention. It is a contributing factor in 30.5% of injury-related deaths among civilians. Additionally, since 2000, more than 260,000 service members were diagnosed with TBI, with the vast majority classified as mild or concussive (76%). The objective assessment of TBI via imaging is a critical research gap, both in the military and civilian communities. In 2011, the Department of Defense (DoD) prepared a congressional report summarizing the effectiveness of seven neuroimaging modalities (computed tomography [CT], magnetic resonance imaging [MRI], transcranial Doppler [TCD], positron emission tomography, single photon emission computed tomography, electrophysiologic techniques [magnetoencephalography and electroencephalography], and functional near-infrared spectroscopy) to assess the spectrum of TBI from concussion to coma. For this report, neuroimag...

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Journal ArticleDOI

Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

Andrew I R Maas, +342 more
- 01 Dec 2017 - 
TL;DR: The InTBIR Participants and Investigators have provided informed consent for the study to take place in Poland.
Journal ArticleDOI

A Review on a Deep Learning Perspective in Brain Cancer Classification

TL;DR: The relationship between brain cancer and other brain disorders like stroke, Alzheimer's, Parkinson's, and Wilson’s disease, leukoriaosis, and other neurological disorders are highlighted in the context of machine learning and the deep learning paradigm.
Journal ArticleDOI

Severe traumatic brain injury: targeted management in the intensive care unit

TL;DR: Progress in monitoring and in understanding pathophysiological mechanisms of TBI could change current management in the intensive care unit, enabling targeted interventions that could ultimately improve outcomes.
Journal ArticleDOI

Glial fibrillary acidic protein elevations relate to neuroimaging abnormalities after mild TBI.

TL;DR: GFAP is confirmed as a promising marker of brain injury in patients with acute mTBI, and a combination of various biomarkers linked to different pathophysiologic mechanisms increases diagnostic subgroup accuracy.
References
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Journal ArticleDOI

Principles of nuclear medicine imaging: planar, SPECT, PET, multi-modality, and autoradiography systems.

TL;DR: The design and operating principles, as well as the capabilities and limitations, of instruments used clinically and preclinically for in vivo radionuclide imaging, including gamma cameras, single-photon emission computed tomography (SPECT) scanners, and positron emissiontomography (PET) scanners are reviewed.
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Immediate computed tomography or admission for observation after mild head injury: cost comparison in randomised controlled trial

TL;DR: Patients with mild head injury attending an emergency department can be managed more cost effectively with computed tomography rather than admission for observation in hospital.
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Relationships among cerebral perfusion pressure, autoregulation, and transcranial Doppler waveform: a modeling study

TL;DR: Model results indicate that only a comparative analysis of the concomitant changes in ultrasonographic quantities during multimodality monitoring may permit the assessment of several aspects of intracranial dynamics (cerebral blood flow changes, vascular pulsatility, ICP changes, intrac Cranial compliance, CPP, and autoregulation).
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Injury-specific correlates of combat-related traumatic brain injury in Operation Iraqi Freedom.

TL;DR: Most incidents of TBI occurring during Operation Iraqi Freedom are mild in severity and a result of blast mechanisms, and multiple injuries were common, particularly as severity of T BI increased.
Journal ArticleDOI

ACR white paper on radiation dose in medicine: Three years later

TL;DR: The ACR, an advocate for radiation safety since its inception in 1924, convened the ACR Blue Ribbon Panel on Radiation Dose in Medicine in 2006 and issued 37 recommendations for the College to address these issues and the status of these recommendations are updated.
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