A Review of the Effectiveness of Neuroimaging Modalities for the Detection of Traumatic Brain Injury
Franck Amyot,David B. Arciniegas,Brazaitis Mp,Curley Kc,Ramon Diaz-Arrastia,Amir H. Gandjbakhche,Herscovitch P,Hinds Sr nd,Geoffrey T. Manley,Anthony Pacifico,Razumovsky A,Jason D. Riley,Salzer W,Shih R,James G. Smirniotopoulos,Stocker D +15 more
TLDR
Although CT, MRI, and TCD were determined to be the most useful modalities in the clinical setting, no single imaging modality proved sufficient for all patients due to the heterogeneity of TBI; all imaging modalities reviewed demonstrated the potential to emerge as part of future clinical care.Abstract:
The incidence of traumatic brain injury (TBI) in the United States was 3.5 million cases in 2009, according to the Centers for Disease Control and Prevention. It is a contributing factor in 30.5% of injury-related deaths among civilians. Additionally, since 2000, more than 260,000 service members were diagnosed with TBI, with the vast majority classified as mild or concussive (76%). The objective assessment of TBI via imaging is a critical research gap, both in the military and civilian communities. In 2011, the Department of Defense (DoD) prepared a congressional report summarizing the effectiveness of seven neuroimaging modalities (computed tomography [CT], magnetic resonance imaging [MRI], transcranial Doppler [TCD], positron emission tomography, single photon emission computed tomography, electrophysiologic techniques [magnetoencephalography and electroencephalography], and functional near-infrared spectroscopy) to assess the spectrum of TBI from concussion to coma. For this report, neuroimag...read more
Citations
More filters
Journal ArticleDOI
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Andrew I R Maas,David K. Menon,P. David Adelson,Nada Andelic,Michael J. Bell,Antonio Belli,Peter Bragge,Alexandra Brazinova,Andras Buki,Randall M. Chesnut,Giuseppe Citerio,Mark Coburn,D. Jamie Cooper,A Tamara Crowder,Endre Czeiter,Marek Czosnyka,Ramon Diaz-Arrastia,Jens P. Dreier,Ann-Christine Duhaime,Ari Ercole,Thomas A. van Essen,Valery L. Feigin,Guoyi Gao,Joseph T. Giacino,Laura E. Gonzalez-Lara,Russell L. Gruen,Russell L. Gruen,Deepak Gupta,Jed A. Hartings,Sean Hill,Jiyao Jiang,Naomi Ketharanathan,Erwin J. O. Kompanje,Linda Lanyon,Steven Laureys,Fiona Lecky,Harvey S. Levin,Hester F. Lingsma,Marc Maegele,Marek Majdan,Geoffrey T. Manley,Jill A. Marsteller,Luciana Mascia,Charles McFadyen,Stefania Mondello,Virginia F. J. Newcombe,Aarno Palotie,Aarno Palotie,Aarno Palotie,Paul M. Parizel,Wilco C. Peul,James Piercy,Suzanne Polinder,Louis Puybasset,Todd E. Rasmussen,Rolf Rossaint,Peter Smielewski,Jeannette Söderberg,Simon J. Stanworth,Murray B. Stein,Nicole von Steinbüchel,William Stewart,Ewout W. Steyerberg,Ewout W. Steyerberg,Nino Stocchetti,Anneliese Synnot,Anneliese Synnot,Braden Te Ao,Olli Tenovuo,Alice Theadom,Dick Tibboel,Walter Videtta,Kevin K.W. Wang,W. Huw Williams,Lindsay Wilson,Kristine Yaffe,Hadie Adams,Vanni Agnoletti,Judith Allanson,Krisztina Amrein,Norberto Andaluz,Audny Anke,Anna Antoni,Arjan Bastiaan van As,Gérard Audibert,Antun Azaševac,Philippe Azouvi,Maria Luisa Azzolini,Camelia Baciu,Rafael Badenes,Karen M. Barlow,Ronald H. M. A. Bartels,Ursula Bauerfeind,Miriam H. Beauchamp,Darcy Beer,Ronny Beer,Francisco Javier Belda,Bo-Michael Bellander,Rémy Bellier,Habib Benali,Thierry Benard,Valzerda Beqiri,Luigi Beretta,Francis Bernard,Guido Bertolini,Federico Bilotta,Morten Blaabjerg,Hugo den Boogert,Kathy Boutis,Pierre Bouzat,Brian L. Brooks,Camilla Brorsson,Monika Bullinger,Emma Burns,Calappi E,Peter Cameron,Elsa Carise,Ana M. Castaño-Leon,Francesco Causin,Giorgio Chevallard,Arturo Chieregato,Brian R. Christie,Maryse C. Cnossen,Jonathan P. Coles,Johnny Collett,Francesco Della Corte,William Craig,Gábor Csató,Ákos Csomós,Nicola Curry,Claire Dahyot-Fizelier,Helen Dawes,Carol DeMatteo,Bart Depreitere,Deborah Dewey,Jeroen T. J. M. van Dijck,Đula Đilvesi,Diederik W.J. Dippel,Kemal Dizdarevic,Emma Donoghue,Or Duek,Guy-Loup Dulière,Adelaida Dzeko,George A. Eapen,Carolyn A. Emery,Shane W. English,Patrick Esser,Erzsébet Ezer,Martin Fabricius,Junfeng Feng,Dean Fergusson,Anthony Figaji,Joanne Fleming,Kelly A Foks,G. Francony,Stephen B. Freedman,Ulderico Freo,Shirin Frisvold,Isabelle Gagnon,Damien Galanaud,Dashiell Gantner,Benoit Giraud,Ben Glocker,Jagos Golubovic,Pedro A Gómez López,Wayne A. Gordon,Primoz Gradisek,Jocelyn Gravel,Donald E. G. Griesdale,Francesca Grossi,Juanita A. Haagsma,Asta Håberg,Iain K. Haitsma,Wim Van Hecke,Raimund Helbok,Eirik Helseth,Caroline M. van Heugten,Cornelia W. E. Hoedemaekers,Stefan Höfer,Lindsay Horton,Jiyuan Hui,Jilske A Huijben,Peter J. Hutchinson,Bram Jacobs,Mathieu van der Jagt,Stefan Jankowski,Koen Janssens,Bojan Jelaca,Kelly Jones,Konstantinos Kamnitsas,Rafael Kaps,Mladen Karan,Ari Katila,Kirsi-Maija Kaukonen,Véronique De Keyser,Riku Kivisaari,Angelos G. Kolias,Balint Kolumban,Ksenija Kolundžija,Daniel Kondziella,Lars-Owe D. Koskinen,Noémi Kovács,Andreas H. Kramer,Demitri Kutsogiannis,Theodoros Kyprianou,Alfonso Lagares,Francois Lamontagne,Roberto Latini,François Lauzier,Isaac Lazar,Christian Ledig,Rolf Lefering,Valerie Legrand,Leon Levi,Roger Lightfoot,Angels Lozano,Stephen MacDonald,Sebastian Major,Alex Manara,Pauline Manhes,Hugues Maréchal,Costanza Martino,Alessandro Masala,Serge Masson,Julia Mattern,Bradford J. McFadyen,Catherine McMahon,Maureen O. Meade,Béla Melegh,Tomas Menovsky,Lynne Moore,Marta M Correia,Maria Cristina Morganti-Kossmann,Holger Muehlan,Pratik Mukherjee,Lynnette Murray,Joukje van der Naalt,Ancuta Negru,David W. Nelson,Daan Nieboer,Quentin Noirhomme,József Nyirádi,Mauro Oddo,David O. Okonkwo,Annemarie W. Oldenbeuving,Fabrizio Ortolano,Martin H. Osmond,Jean-François Payen,Vincent Perlbarg,Paolo Persona,Nicolas Pichon,Anna Piippo-Karjalainen,Sebastien Pili-Floury,Matti Pirinen,Horia Ple,Maria A. Poca,Jussi P. Posti,Dominique Van Praag,Alain Ptito,Andreea Radoi,Arminas Ragauskas,Arminas Ragauskas,Rahul Raj,Ruben G. L. Real,Nick Reed,Jonathan Rhodes,Claudia S. Robertson,Saulius Rocka,Saulius Rocka,Cecilie Røe,Olav Røise,Gerwin Roks,Jonathan Rosand,Jeffrey V. Rosenfeld,Christina Rosenlund,Guy Rosenthal,Sandra Rossi,Daniel Rueckert,Godard C.W. de Ruiter,Marco Sacchi,Barbara J. Sahakian,Juan Sahuquillo,Oliver W. Sakowitz,Gerardo Salvato,Renán Sánchez-Porras,János Sándor,Grinder Sangha,Nadine Schäfer,Silke Schmidt,Kathryn J Schneider,David M. Schnyer,Herbert Schöhl,Guus G. Schoonman,Rico Frederik Schou,Özcan Sir,Toril Skandsen,Dirk Smeets,Abayomi Sorinola,Emmanuel Stamatakis,Ana Stevanovic,Robert Stevens,Nina Sundström,Fabio Silvio Taccone,Fabio Silvio Taccone,Riikka S.K. Takala,Päivi Tanskanen,Mark Taylor,Ralph Telgmann,Nancy R. Temkin,Guido Teodorani,Matthew Thomas,Christos M. Tolias,Tony Trapani,Alexis F. Turgeon,Peter Vajkoczy,Alex B. Valadka,Egils Valeinis,Shirley Vallance,Zoltan Vamos,Alessia Vargiolu,Emmanuel Vega,Jan Verheyden,Anne Vik,Rimantas Vilcinis,Carmen L.A. Vleggeert-Lankamp,Lidia Vogt,Victor Volovici,Daphne C. Voormolen,Peter Vulekovic,Thijs Vande Vyvere,Julia Van Waesberghe,Lars Wessels,Eno Wildschut,Guy B. Williams,Maren K.L. Winkler,Stefan Wolf,Gordon Wood,Nektaria Xirouchaki,Alexander Younsi,Menashe Zaaroor,Veronika Zelinkova,Roger Zemek,Fabrizio Zumbo +342 more
TL;DR: The InTBIR Participants and Investigators have provided informed consent for the study to take place in Poland.
Journal ArticleDOI
A Review on a Deep Learning Perspective in Brain Cancer Classification
Gopal S. Tandel,Mainak Biswas,Omprakash Kakde,Ashish Tiwari,Harman S. Suri,Monica Turk,John R. Laird,Christopher Kwaku Asare,Annabel A. Ankrah,Narendra N. Khanna,B. K. Madhusudhan,Luca Saba,Jasjit S. Suri +12 more
TL;DR: The relationship between brain cancer and other brain disorders like stroke, Alzheimer's, Parkinson's, and Wilson’s disease, leukoriaosis, and other neurological disorders are highlighted in the context of machine learning and the deep learning paradigm.
Journal ArticleDOI
Severe traumatic brain injury: targeted management in the intensive care unit
Nino Stocchetti,Nino Stocchetti,Marco Carbonara,Giuseppe Citerio,Ari Ercole,Markus B. Skrifvars,Markus B. Skrifvars,Peter Smielewski,Tommaso Zoerle,David K. Menon +9 more
TL;DR: Progress in monitoring and in understanding pathophysiological mechanisms of TBI could change current management in the intensive care unit, enabling targeted interventions that could ultimately improve outcomes.
Journal ArticleDOI
Glial fibrillary acidic protein elevations relate to neuroimaging abnormalities after mild TBI.
Jessica Gill,Lawrence L. Latour,Ramon Diaz-Arrastia,Vida Motamedi,Christine Turtzo,Pashtun Shahim,Stefania Mondello,Christina Devoto,Eliseo Veras,David Hanlon,Linan Song,Andreas Jeromin +11 more
TL;DR: GFAP is confirmed as a promising marker of brain injury in patients with acute mTBI, and a combination of various biomarkers linked to different pathophysiologic mechanisms increases diagnostic subgroup accuracy.
Journal ArticleDOI
Sleep, Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group
Emerson M. Wickwire,Scott G. Williams,Scott G. Williams,Thomas Roth,Vincent F. Capaldi,Michael Jaffe,Margaret Moline,Gholam K. Motamedi,Gregory W. Morgan,Vincent Mysliwiec,Vincent Mysliwiec,Anne Germain,Renee M. Pazdan,Reuven Ferziger,Thomas J. Balkin,Margaret E. MacDonald,Thomas A. Macek,Michael R. Yochelson,Steven M. Scharf,Christopher J. Lettieri +19 more
TL;DR: Key findings from a national working group on sleep and TBI are presented, with a specific focus on the testing and development of sleep-related therapeutic interventions for mild TBI (mTBI).
References
More filters
Journal ArticleDOI
Widespread and prolonged increase in (R)-(11)C-PK11195 binding after traumatic brain injury.
Hedy Folkersma,Ronald Boellaard,Maqsood Yaqub,Reina W. Kloet,Albert D. Windhorst,Adriaan A. Lammertsma,W. Peter Vandertop,Bart N.M. van Berckel +7 more
TL;DR: There was a prolonged and widespread increase in (R)-11C-PK11195 binding, which is indicative of diffuse neuronal damage after traumatic brain injury, six months after TBI.
Journal ArticleDOI
F-18 FDG PET imaging of chronic traumatic brain injury in boxers: a statistical parametric analysis.
Frank A. Provenzano,Barry D. Jordan,Ronald S. Tikofsky,Chitra Saxena,Ronald L. Van Heertum,Masanori Ichise +5 more
TL;DR: The results suggest that F-18 FDG PET scans of boxers suspected of chronictraumatic brain injury show unique patterns of hypometabolism, and that these patterns may reflect the mechanisms of repeated traumatic brain injury unique to boxers.
Journal ArticleDOI
Procedure guideline for brain perfusion SPECT using (99m)Tc radiopharmaceuticals 3.0.
Jack E. Juni,Alan D. Waxman,Michael D. Devous,Ronald S. Tikofsky,Masanori Ichise,Ronald L. Van Heertum,Robert F. Carretta,Charles C. Chen +7 more
TL;DR: This list of hospitals and clinics in the United States and Canada that provide medical care to seriously ill and injured patients has been compiled.
Journal Article
Acute Changes in Regional Cerebral 18F-FDG Kinetics in Patients with Traumatic Brain Injury
Naoya Hattori,Sung-Cheng Huang,Hsiao-Ming Wu,Wei-Hsun Liao,Thomas C. Glenn,Paul M. Vespa,Michael E. Phelps,David A. Hovda,Marvin Bergsneider +8 more
TL;DR: Brain tissue (18)F-FDG kinetics in TBI patients were consistent with reduced hexokinase activity in the whole brain (including apparently uninjured cortex), whereas glucose transport was impaired only in the area immediately around the contusion.
Journal ArticleDOI
Cognitive functions in relation to MRI findings 30 years after traumatic brain injury.
TL;DR: The results show that long-term memory impairments after TBI are associated with MRI volumetric measures, which suggests that the degree of diffuse injury leading to atrophic changes is prognostically more important than the initial severity of TBI.