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Journal ArticleDOI

Ablation for longstanding permanent atrial fibrillation: Results from a randomized study comparing three different strategies

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TLDR
The hybrid AF ablation strategy including antrum isolation and CFAE ablation had the highest likelihood of maintaining sinus rhythm in patients with longstanding permanent AF.
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This article is published in Heart Rhythm.The article was published on 2008-12-01. It has received 310 citations till now. The article focuses on the topics: Longstanding persistent atrial fibrillation & Sinus rhythm.

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Citations
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Journal ArticleDOI

Approaches to Catheter Ablation for Persistent Atrial Fibrillation

TL;DR: Among patients with persistent atrial fibrillation, there was no reduction in the rate of recurrent atrialfibrillation when either linear ablation or ablation of complex fractionated electrograms was performed in addition to pulmonary-vein isolation.
Journal ArticleDOI

Approaches to catheter ablation of persistent atrial fibrillation

TL;DR: Further efforts are needed to develop better techniques and tools to safely, effectively, and permanently isolate the PV antra, to identify which sites are critical to the maintence of AF, and to create durable transmural linear lesions to interrupt intraatrial reentry.
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Outcomes of long-standing persistent atrial fibrillation ablation: a systematic review.

TL;DR: The variation in success within and between techniques suggests that the optimal ablation technique for long-standing persistent AF is unclear.
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Catheter ablation of long-standing persistent atrial fibrillation: 5-year outcomes of the Hamburg Sequential Ablation Strategy.

TL;DR: During 5-year follow-up, single- and multiple ablation procedure success was 20% and 45%, respectively, for patients with LS-AF, and For patients with a total AF duration of <2 years, the outcomes were favorable.
References
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Journal ArticleDOI

Spontaneous Initiation of Atrial Fibrillation by Ectopic Beats Originating in the Pulmonary Veins

TL;DR: The pulmonary veins are an important source of ectopic beats, initiating frequent paroxysms of atrial fibrillation and these foci respond to treatment with radio-frequency ablation.
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A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate

TL;DR: Testing the hypothesis that complex fractionated electrograms recorded during atrial fibrillation could be used as target sites for catheter ablation of AF found areas with CFAEs represent a defined electrophysiologic substrate and are ideal target Sites for ablations to eliminate AF and maintain normal sinus rhythm.
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Circumferential Radiofrequency Ablation of Pulmonary Vein Ostia A New Anatomic Approach for Curing Atrial Fibrillation

TL;DR: In this paper, the authors developed an anatomic approach aimed at isolating each pulmonary vein from the left atrium (LA) by circumferential radiofrequency (RF) lesions around their ostia.
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Pulmonary Vein Isolation for Paroxysmal and Persistent Atrial Fibrillation

TL;DR: The clinical efficacy of pulmonary vein isolation is much lower when AF is persistent than when it is paroxysmal, and with a segmental isolation approach that targets at least 3 PVs, a clinically satisfactory result can be achieved in >80% of patients with paroxYSmal AF.
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Circumferential pulmonary-vein ablation for chronic atrial fibrillation.

TL;DR: Sinus rhythm can be maintained long term in the majority of patients with chronic atrial fibrillation by means of circumferential pulmonary-vein ablation independently of the effects of antiarrhythmic-drug therapy, cardioversion, or both.
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