Journal ArticleDOI
Acetylated flavanone glycosides from the rhizomes of Cyclosorus acuminatus.
TLDR
Six new flavanone glycosides were isolated from the methanol extract of the rhizomes of Cyclosorus acuminatus, together with the parent flavan one glycoside 2a, and showed moderate activity against Streptococcus pneumoniae and Haemophilus influenzae.Abstract:
Six new flavanone glycosides (1-6) were isolated from the methanol extract of the rhizomes of Cyclosorus acuminatus, together with the parent flavanone glycoside 2a. Their structures were established on the basis of spectroscopic and chemical methods. All compounds showed moderate activity against Streptococcus pneumoniae and Haemophilus influenzae.read more
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Flavonoids and their glycosides, including anthocyanins
Nigel C. Veitch,Renée J. Grayer +1 more
TL;DR: This review describes more than 600 new examples of naturally occurring flavonoids found either as aglycones or glycosides, comprising flavones, flavonols, chalcones, dihydrochalcones and anthocyanidins.
Journal ArticleDOI
Gastroprotective flavonoid constituents from Oroxylum indicum Vent.
T. Hari Babu,K. Manjulatha,G. Suresh Kumar,A. Hymavathi,Ashok Kumar Tiwari,M. C. Purohit,J. Madhusudana Rao,K. Suresh Babu +7 more
TL;DR: Two new flavonoid glycosides are identified in the stem bark of Oroxylum indicum along with seven known compounds, which were tested for their ulcer protective effects against various gastric ulceritis inducing models in rats.
Journal ArticleDOI
Chalcone derivatives from the fern Cyclosorus parasiticus and their anti-proliferative activity.
TL;DR: Three new chalcone derivatives, named parasiticins A-C (1-3), were isolated from the leaves of Cyclosorus parasiticus and demonstrated that compounds 3 and 6 could induce apoptosis in the HepG2 cell line, which may contribute significantly to their cytotoxicity.
Journal ArticleDOI
A novel, broad-spectrum antitumor compound containing the 1-hydroxycyclohexa-2,5-dien-4-one group: The disclosure of a new antitumor pharmacophore in protoapigenone 1
TL;DR: The synthesis of a new compound 10 containing the 4-hydroxy-2,5-cyclohexadien-1-one system showed potent in vitro antitumor potency with low micromolar IC(50)'s against breast, ovarian, prostate, liver, pancreas, and blood cancer cell lines tested and could inhibit tumor growth in vivo but no significant impairment of hematopoiesis or immune function was observed.
Journal ArticleDOI
New CuCl2-induced glucoside esters and other constituents from Portucala oleracea.
TL;DR: The results showed that new stress-driven adducts of monolignans and monoterpenes with a glucose bridge exhibited much stronger antioxidative activities than other compounds.
References
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Circular dichroism, optical rotatory dispersion and absolute configuration of flavanones, 3-hydroxyflavanones and their glycosides : Determination of aglycone chirality in flavanone glycosides☆
TL;DR: In this paper, the 2 S configuration and 3-hydroxy-flavanones of 2 R, 3 R configuration, having equatorial 2-aryl substituents in the former or diequatorial 2,3-substituents of the latter, exhibit a positive Cotton effect due to the n → π * transition (∼ 330 nm) and a negative Cotton effect in the n α π ∆ * region(∼ 280-290 nm).