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Journal ArticleDOI

Adaptive Photoacoustic Sensing Using Matched Filter

TLDR
Wang et al. as mentioned in this paper proposed an adaptive photo-acoustic (aPA) sensing method using matched filter to enhance the detected signal SNR with single laser pulse, which showed the potential of aPA to perform highly sensitive photoacoustic sensing with accelerated sensing and imaging speed.
Abstract
Sensitive detection is always crucial to photoacoustic sensing and imaging applications owing to the extremely low conversion efficiency from light to sound. A conventional approach to enhance the signal-to-noise ratio (SNR) of the photoacoustic signal is data averaging, which is quite time-consuming due to multiple data acquisitions for each photoacoustic measurement. Especially for a high-power pulsed laser source with only a 1020 pulse repetition rate, multiple data averaging will severely degrade the frame rate. In this article, we present a simple but efficient method, called adaptive photoacoustic (aPA) sensing, using matched filter to obviously enhance the detected signal SNR with single laser pulse. Invivo experimental results show that the proposed aPA method improved the signal SNR by about 60dB. It demonstrates the potential of aPA to perform highly sensitive photoacoustic sensing and imaging with accelerated sensing and imaging speed.

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Citations
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Journal ArticleDOI

Review of Low-Cost Photoacoustic Sensing and Imaging Based on Laser Diode and Light-Emitting Diode.

TL;DR: This paper reviews the recent development of the photoacoustic sensing and imaging based on the economical laser sources such as laser diode and light-emitting diode (LED) in different kinds of modulation types, and discusses several representative methods to improve the performance of such imaging systems based on low-cost laser sources.
Journal ArticleDOI

Pushing the boundaries of optoacoustic microscopy by total impulse response characterization.

TL;DR: This work introduces high-quality TIR determination based on spatially-distributed optoacoustic point sources (SOAPs) produced by scanning an optical focus on an axially-translatable 250 nm gold layer and shows that subsequent TIR correction results in improved image quality.
Proceedings ArticleDOI

Wavelet de-noising method with adaptive threshold selection for photoacoustic tomography

TL;DR: This paper proposes a new adaptive wavelet threshold de-noising (aWTD) algorithm, and applies it in photoacoustic tomography to increase the PA signal’s SNR without sacrificing the signal fidelity and imaging speed.
Journal ArticleDOI

De-noising of photoacoustic sensing and imaging based on combined empirical mode decomposition and independent component analysis.

TL;DR: To improve the signal fidelity and imaging speed, an algorithm of using empirical mode decomposition and independent component analysis de-noising methods in PA imaging is proposed and results show obvious SNR enhancement of the PA signal and image contrast.
Journal ArticleDOI

An Improved Moving Tracking Algorithm With Multiple Information Fusion Based on 3D Sensors

TL;DR: The experimental results show that the proposed algorithm can accurately track a moving target in the presence of a complex background, and greatly improves the interference resistance and robustness of the system.
References
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Journal ArticleDOI

Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs

TL;DR: A review of the state of the art of photoacoustic tomography for both biological and clinical studies can be found in this paper, where the authors discuss the current state-of-the-art and discuss future prospects.
Journal ArticleDOI

Photoacoustic imaging in biomedicine

TL;DR: An overview of the rapidly expanding field of photoacoustic imaging for biomedical applications can be found in this article, where a number of imaging techniques, including depth profiling in layered media, scanning tomography with focused ultrasonic transducers, image forming with an acoustic lens, and computed tomography using unfocused transducers are introduced.
Journal ArticleDOI

Biomedical photoacoustic imaging

TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
Journal ArticleDOI

Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging

TL;DR: Functional photoacoustic microscopy (fPAM) is reported, which provides multiwavelength imaging of optical absorption and permits high spatial resolution beyond this depth limit with a ratio of maximum imaging depth to depth resolution greater than 100.
Journal ArticleDOI

Noninvasive laser-induced photoacoustic tomography for structural and functional in vivo imaging of the brain

TL;DR: In vivo noninvasive transdermal and transcranial imaging of the structure and function of rat brains by means of laser-induced photoacoustic tomography (PAT) is reported, which retains intrinsic optical contrast characteristics while taking advantage of the diffraction-limited high spatial resolution of ultrasound.
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