Open Access
Advanced Healthcare Materials
TLDR
The book highlights the key features which enable engineers to design stimuli-responsive smart nanoparticles, novel biomaterials, nano/micro- devices for diagnosis, therapy (theranostics), and up and coming bio-engineering devices.Abstract:
Advanced materials are attracting strong interest in the fundamental as well as applied sciences and are being extensively explored for their potential usage in a range of healthcare technological ...read more
Citations
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Journal ArticleDOI
Graphene-based materials biocompatibility: A review
TL;DR: The distinct physical-chemical nature of the GBMs available is clarified, as well as the production methods involved, and the biocompatibility issues concerning composite materials that incorporate GBMs are addressed.
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Hydrogel Bioink Reinforcement for Additive Manufacturing: A Focused Review of Emerging Strategies.
TL;DR: This bottom‐up perspective provides a materials‐centric approach to bioink design for 3D bioprinting and current and emerging approaches in hydrogel design and bioink reinforcement techniques are critically evaluated.
Journal ArticleDOI
Graphene oxide selectively targets cancer stem cells, across multiple tumor types: implications for non-toxic cancer treatment, via "differentiation-based nano-therapy".
Marco Fiorillo,Marco Fiorillo,Andrea Francesco Verre,Maria Iliut,Maria Peiris-Pagès,Béla Ózsvári,Ricardo Gandara,Anna Rita Cappello,Federica Sotgia,Aravind Vijayaraghavan,Michael P. Lisanti +10 more
TL;DR: Graphene oxide is shown to be an effective non-toxic therapeutic strategy for the eradication of cancer stem cells, via differentiation-based nano-therapy and Mechanistically, it is presented evidence that GO exerts its striking effects on CSCs by inhibiting several key signal transduction pathways and thereby inducing CSC differentiation.
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A microengineered pathophysiological model of early-stage breast cancer
Yoon-Seok Choi,Eunjeh Hyun,Jeongyun Seo,Cassidy Blundell,Hee Chan Kim,Eun Hee Lee,Su Hyun Lee,Aree Moon,Woo Kyung Moon,Dongeun Huh +9 more
TL;DR: This microengineered disease model represents the first critical step towards recapitulating pathophysiological complexity of breast cancer, and may serve as an enabling tool to systematically examine the contribution of the breast cancer microenvironment to the progression of DCIS to an invasive form of the disease.
Journal ArticleDOI
Flexible pH-Sensing Hydrogel Fibers for Epidermal Applications
Ali Tamayol,Ali Tamayol,Mohsen Akbari,Yael Zilberman,Mattia Comotto,Mattia Comotto,Emal Lesha,Emal Lesha,Ludovic Serex,Ludovic Serex,Sara Bagherifard,Sara Bagherifard,Sara Bagherifard,Yu Chen,Guoqing Fu,Shideh Kabiri Ameri,Weitong Ruan,Eric L. Miller,Mehmet R. Dokmeci,Mehmet R. Dokmeci,Mehmet R. Dokmeci,Sameer Sonkusale,Ali Khademhosseini +22 more
TL;DR: Here, pH‐responsive hydrogel fibers are presented that can be used for long‐term monitoring of epidermal wound condition and can act as a point‐of‐care device for monitoring the wound healing process.
Related Papers (2)
25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine
Nasim Annabi,Nasim Annabi,Ali Tamayol,Ali Tamayol,Jorge Alfredo Uquillas,Jorge Alfredo Uquillas,Mohsen Akbari,Mohsen Akbari,Luiz E. Bertassoni,Luiz E. Bertassoni,Chaenyung Cha,Chaenyung Cha,Gulden Camci-Unal,Gulden Camci-Unal,Mehmet R. Dokmeci,Mehmet R. Dokmeci,Nicholas A. Peppas,Ali Khademhosseini,Ali Khademhosseini +18 more