Journal ArticleDOI
Affective neuroscientific and neuropsychoanalytic approaches to two intractable psychiatric problems: why depression feels so bad and what addicts really want.
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TLDR
The affective foundations of depression and addictions are discussed from a cross-species - animal to human - perspective of translational psychiatric research, imagining the foundation of such psychiatric problems as being in imbalances of the basic mammalian emotional systems that engender prototype affective states may provide more robust translational research strategies.About:
This article is published in Neuroscience & Biobehavioral Reviews.The article was published on 2011-10-01. It has received 92 citations till now. The article focuses on the topics: Dysphoria & Addiction.read more
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Rapid effects of deep brain stimulation for treatment-resistant major depression.
TL;DR: Preliminary findings suggest that bilateral stimulation of the supero-lateral branch of the medial forebrain bundle may significantly reduce symptoms in treatment-resistant major depressive disorder.
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The basic emotional circuits of mammalian brains: do animals have affective lives?
TL;DR: Since all vertebrates appear to have some capacity for primal affective feelings, the implications for animal-welfare and how the authors ethically treat other animals are vast.
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The SEEKING mind: Primal neuro-affective substrates for appetitive incentive states and their pathological dynamics in addictions and depression
Antonio Alcaro,Jaak Panksepp +1 more
TL;DR: Abnormal manifestation of SEEKING and its neural substrates are evident in clinical depression and addiction, while addictions reflect re-organizations of the SEEKING disposition around ultra-specific appetitive memories and compulsive activities.
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Affective neuroscience of the emotional BrainMind: evolutionary perspectives and implications for understanding depression.
TL;DR: Advances in the understanding of the nature of primary-process emotional affects can promote the development of better preclinical models of psychiatric disorders and thereby also allow clinicians new and useful ways to understand the foundational aspects of their clients' problems.
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The roles of the reward system in sleep and dreaming.
TL;DR: The Reward Activation Model (RAM) for sleep and dreaming is introduced, according to which activation of the ML-DA reward system during sleep contributes to memory processes, to the regulation of rapid-eye movement (REM) sleep, and to the generation and motivational content of dreams.
References
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Book
The Standard Edition of the Complete Psychological Works of Sigmund Freud
TL;DR: The Complete Psychological Works of Sigmund Freud in English as mentioned in this paper is the first full paperback publication of the standard edition of the complete psychological works in English, containing twenty-four volumes.
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Mourning and Melancholia
TL;DR: Freud, S. as discussed by the authors, The Complete Psychological Works of Sigmund Freud, Volume XIV (1914-1916): On the History of the Psycho-Analytic Movement, Papers on Metapsychology and Other Works, 237-258 Mourning and Melancholia, 237.
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Affective Neuroscience: The Foundations of Human and Animal Emotions
TL;DR: In this article, a conceptual framework for the neurobiological analysis of affect is presented, based on the concepts of affective neuroscience and affective operating systems, and subjectivity.
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Beyond the Pleasure Principle
TL;DR: The Standard Edition of the Complete Psychological Works of Sigmund Freud under the general editorship of James Strachey as discussed by the authors was the first English translation of Freud's major works to appear in his lifetime.