Journal ArticleDOI
Aging and changes in phasic events during sleep
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TLDR
There is a marked variability among individuals in the number of spindles and K-complexes and more so in older individuals than in younger, however, there is an overall decrease in these events with age.About:
This article is published in Physiology & Behavior.The article was published on 1993-10-01. It has received 62 citations till now. The article focuses on the topics: Non-rapid eye movement sleep & Sleep Stages.read more
Citations
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Journal ArticleDOI
Sleep spindles: an overview
Luigi De Gennaro,Michele Ferrara +1 more
TL;DR: This review summarizes the present knowledge on visually scored and automatically detected spindles, as well as the literature on EEG power in the sigma band, and discusses the role of melatonin as a spindle-promoting agent and the relationships between plastic mechanisms.
Journal ArticleDOI
Effect of age on the sleep EEG: slow-wave activity and spindle frequency activity in young and middle-aged men.
TL;DR: It is concluded that frequency and state specific changes occur as a function of age, and that sleep dependent decline in SWA and increase in sleep spindle activity are attenuated with age.
Journal ArticleDOI
Sleep and quantitative EEG in neurodegenerative disorders
Dominique Petit,Jean-François Gagnon,Maria Livia Fantini,Luigi Ferini-Strambi,Jacques Montplaisir +4 more
TL;DR: Current knowledge on sleep problems, sleep architecture changes and quantitative EEG alteration brought on by various neurodegenerative diseases, such as Alzheimer's disease, progressive supranuclear palsy, REM sleep behavior disorder, and dementia with Lewy bodies are reviewed.
Journal ArticleDOI
The effects of normal aging on sleep spindle and K-complex production.
Kate E. Crowley,Kate E. Crowley,John Trinder,Young Kim,Melinda Carrington,Ian M. Colrain,Ian M. Colrain +6 more
TL;DR: The age-related decrease in sleep spindles and K-complex density is consistent with previous reports and may be interpreted as an age- related alteration of thalamocortical regulatory mechanisms.
Journal ArticleDOI
Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia ☆
TL;DR: In older adults with chronic insomnia, ramelteon significantly reduced patient reports of sleep latency over five weeks of treatment with no significant rebound insomnia or withdrawal effects.
References
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Journal ArticleDOI
Human aging: usual and successful
John W. Rowe,Robert L. Kahn +1 more
TL;DR: Research on the risks associated with usual aging and strategies to modify them should help elucidate how a transition from usual to successful aging can be facilitated.
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Admission criteria for immunogerontological studies in man: the SENIEUR protocol.
G. J. Ligthart,Joel X. Corberand,Catherine Fournier,P Galanaud,W. Hijmans,Bernard Kennes,Hans K. Müller-Hermelink,Gerhard G. Steinmann +7 more
TL;DR: Findings in the immunologically "optimally aged" can also serve as reference values for immunogerontological studies in subjects who do not meet the SENIEUR criteria, and can contribute to the dissection of the influence of disease versus ageing on the immune system.
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Changes in sleep cycle patterns with age
Irwin Feinberg,Irwin Feinberg +1 more
TL;DR: An analysis of data by sleep cycle was carried out for the main variables concerning sleep with EEG slow waves, sleep with rapid eye movements, and awakenings, and it was suggested that the trends in sleep pattern across the night have significant implications for the brain processes which underlie the electrophysiological manifestations of sleep.
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EEG sleep patterns as a function of normal and pathological aging in man
Irwin Feinberg,Irwin Feinberg,Richard L. Koresko,Richard L. Koresko,Naomi Heller,Naomi Heller +5 more
TL;DR: It appears that the EEG of sleep may prove to be a diagnostic and research tool of special value to geriatric psychiatry because the quantitative changes in sleep with normal and pathological aging are similar to changes which take place in rate of overall brain metabolism.