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Alcoholism IV. Is there more than one type of alcoholism

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TLDR
Suicide attempts were significantly more frequently seen among the affective-disorder-alcoholic women than among the primary alcoholic women and there was significantly more affective disorder in the families of affected women than in those of the primary alcoholics.
Abstract
Two hundred and fifty-nine alcoholics have been studied clinically. In addition, family histories of psychiatric illness were obtained and 507 first degree relatives were personally. interviewed. Clinically, there are three major groups of alcoholics, (1) primary alcoholics, (2) depression alcoholics and (3) sociopathy-alcoholics. Males predominate in the first and third groups; females in the second group. In first degree family members, alcoholism is more frequently seen for the primary alcoholism group, depression for the depression alcoholism group and sociopathy for the sociopathy-alcoholism group. Nevertheless, for various classes of relatives this kind of segregation does not stay consistent. In all three groups similar percentages of first degree relatives have alcoholism or depression. However, most ill male relatives have alcoholism, and most ill females have depression. The data may indicate three types of alcoholism, or alternatively the possibility that males and females differ in the way they express the illness. Because of the inconsistency in the various classes of relatives, the latter interpretation is probably correct, i.e., that in families of alcoholic probands, ill female relatives express their illness mostly by depression and sometimes by alcoholism, and ill male relatives express their illness mostly by alcoholism and sometimes by depression.

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Citations
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Sex differences in unipolar depression: evidence and theory.

TL;DR: It is suggested that differences in the ways that men and women respond to their own depressive episodes, whatever the origin of these episodes, may be an important source of the sex differences observed in depression.
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Types of alcoholics, I. Evidence for an empirically derived typology based on indicators of vulnerability and severity.

TL;DR: An empirical clustering technique was applied to data obtained from 321 male and female alcoholics to identify homogeneous subtypes having discriminative and predictive validity and suggest that an empirically derived, multivariate typology of alcoholism has theoretical implications for explaining the heterogeneity among alcoholics and may provide a useful basis for predicting course and estimating treatment response.
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Psychopathology as a predictor of treatment outcome in alcoholics.

TL;DR: The value of determining psychiatric diagnosis was supported by covariance analyses that suggested that prognostic significance of specific disorders was not accounted for by general psychopathology or general dependence dimensions.
Journal ArticleDOI

Implications of Sex Differences in the Prevalences of Antisocial Personality, Alcoholism, and Criminality for Familial Transmission

TL;DR: Three multifactorial models of disease transmission in which the prevalences of a disease differ in men and women are described to demonstrate explicitly how such sex differences may be caused by genetic factors, home environment, sociocultural, or other nonfamilial factors.
References
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Alcoholism: III. Diagnosis and Familial Psychiatric Illness in 259 Alcoholic Probands

TL;DR: Among the first-degree relatives of the alcoholic probands psychopathy was increased when compared to general population figures and brothers and fathers of male alcoholics showed considerably more alcoholism than would be expected.
Journal ArticleDOI

Alcoholism: I. Two Types of Alcoholism in Women

TL;DR: The purpose of this paper is to describe an attempt to delineate alcoholism into nosologically homogeneous groups and to limit the present discussion to alcoholism in the female.
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