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Journal ArticleDOI

Alginate and chitosan polyion complex hybrid fibers for scaffolds in ligament and tendon tissue engineering

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TLDR
Alginate-based chitosan hybrid polymer fibers showed much improved adhesion capacity with fibroblast compared with alginate polymer fiber, and had considerable potential as a desirable biomaterial scaffold for tendon and ligament tissue engineering.
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This article is published in Journal of Orthopaedic Science.The article was published on 2005-05-01. It has received 186 citations till now. The article focuses on the topics: Fiber & Chitosan.

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Journal ArticleDOI

Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications

TL;DR: Several selected pharmaceutical and biomedical applications are presented, in which chitin and chitosan are recognized as new biomaterials taking advantage of their biocompatibility and biodegradability.
Journal ArticleDOI

Stem cell-based tissue engineering with silk biomaterials.

TL;DR: Stem cell-based tissue engineering using 3D silk fibroin scaffolds has expanded the use of silk-based biomaterials as promising scaffolds for engineering a range of skeletal tissues like bone, ligament, and cartilage, as well as connective tissues like skin.
Journal ArticleDOI

Main properties and current applications of some polysaccharides as biomaterials

TL;DR: The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan, hyaluronan, and alginates.
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Chitin and Chitosan in Selected Biomedical Applications

TL;DR: An overview of the key features of CT and CS membranes and scaffolds such as their biodegradability, cytocompatibility and mechanical properties toward applications in tissue engineering and wound healing are provided.
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Nontraumatic osteonecrosis of the femoral head: ten years later.

TL;DR: The results of joint-preserving procedures are less satisfactory than the results of total hip arthroplasty for femoral heads that have already collapsed, and new pharmacological measures as well as the use of growth and differentiation factors for the prevention and treatment of this disease may eventually alter the treatment approach.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Biological interactions between polysaccharides and divalent cations: The egg‐box model

TL;DR: It is shown that spedfic binding of divalent cations to a polysaechafide polyelectro]ym, leading firm cohesion between the chains, can cause characteristic effects in the c~rcutar diehroism spectrum which are understandabb in terms of modem theo~, [ l ].
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Porous chitosan scaffolds for tissue engineering

TL;DR: The methods and structures described here provide a starting point for the design and fabrication of a family of polysaccharide based scaffold materials with potentially broad applicability in several tissue-relevant geometries.
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Tensile properties of the human femur-anterior cruciate ligament-tibia complex: The effects of specimen age and orientation

TL;DR: Values found when the femur- ACL-tibia complex was tested in the anatomical orientation were higher than those reported previously in the literature and provide new baseline data for the design and selection of grafts for ACL replacement in an attempt to reproduce normal knee kinematics.
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Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function.

TL;DR: This review focuses on the extracellular proteoglycans, with special emphasis on the structural features of their protein cores, their gene organization, and their transcriptional control.
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