Journal ArticleDOI
Alleviation of diabetes mellitus through the restoration of β-cell function and lipid metabolism by Aloe vera (L.) Burm. f. extract in obesogenic WNIN/GR-Ob rats.
Neha Deora,M.M. Sunitha,M. Satyavani,N. Harishankar,Mookambeswaran A. Vijayalakshmi,Krishnan Venkataraman,Vijayalakshmi Venkateshan +6 more
TLDR
In this article, the authors investigated the simultaneous effect of ethanolic A. vera gel extract on diabetes and obesogenic milieu in Streptozotocin-induced WNIN/GR-Ob mutant obese rats.About:
This article is published in Journal of Ethnopharmacology.The article was published on 2021-05-23. It has received 12 citations till now. The article focuses on the topics: Insulin resistance & Diabetes mellitus.read more
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Synergistic effect of Aloe vera flower and Aloe gel on cutaneous wound healing targeting MFAP4 and its associated signaling pathway: In-vitro study.
TL;DR: Wang et al. as mentioned in this paper investigated the synergistic effect of A. vera flower and Aloe gel in cutaneous wound healing, cell viability, and cell migration, as well proliferation assay was performed.
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Supplementation of conventional anti-diabetic therapy with alpha-lipoic acid prevents early development and progression of diabetic nephropathy.
George J. Dugbartey,Karl K. Alornyo,Benoit Banga N'guessan,Stephen Atule,Samuel De Graft Mensah,Samuel Adjei +5 more
TL;DR: In this paper , Alpha-lipoic acid (ALA) was used to prevent early development and progression of Type 2 diabetes mellitus (T2DM) in male Sprague-Dawley rats.
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Genus Aloe as sources of antidiabetic, antihyperglycemic and hypoglycemic agents: A review
Mutiu Idowu Kazeem,H. A. Bankole,Azeez A. Fatai,Gbemisola Morounke Saibu,Adedoja Dorcas Wusu +4 more
TL;DR: In this paper , the authors integrated available information on all Aloe spp. with antidiabetic potentials and found that the most common species of Aloe sp. is A. vera and few studies were carried out in vitro while most were performed in vivo.
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Natural products for the treatment and management of diabetes mellitus in Zimbabwe-a review
TL;DR: A number of studies carried out to evaluate the antidiabetic properties of indigenous plants found in Zimbabwe with the goal of treating diabetes mellitus are highlighted and can open pathways leading to discovery of new plant derived medicines and regularization of use of crude plant remedies.
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Homalium zeylanicum attenuates streptozotocin-induced hyperglycemia and cellular stress in experimental rats via attenuation of oxidative stress imparts inflammation
TL;DR: In this article, the authors investigated in vitro and in vivo glycemic response of homalium zeylanicum (Gardner Benth (Salicaceae) leaves, and evaluation of possible mechanism of bioactive molecules in mitigating streptozotocin-induced cellular stress in experimental rats via attenuation of oxidative stress imparts inflammation.
References
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Obesity and Diabetes in the Developing World — A Growing Challenge
TL;DR: Propelling an upsurge in cases of diabetes and hypertension is the growing prevalence of overweight and obesity.
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Dyslipidemia in Obesity: Mechanisms and Potential Targets
TL;DR: An important link between obesity, the metabolic syndrome and dyslipidemia, seems to be the development of insulin resistance in peripheral tissues leading to an enhanced hepatic flux of fatty acids from dietary sources, intravascular lipolysis and from adipose tissue resistant to the antilipolytic effects of insulin.
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Use of metabolic markers to identify overweight individuals who are insulin resistant.
TL;DR: The prevalence of insulin resistance is increased in patients with type 2 diabetes mellitus, essential hypertension, and CVD and that insulin resistance and compensatory hyperinsulinemia have been shown to be independent predictors of all 3 clinical syndromes.
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The plant kingdom as a source of anti‐ulcer remedies
TL;DR: Despite progress in conventional chemistry and pharmacology in producing effective drugs, the plant kingdom might provide a useful source of new anti‐ulcer compounds for development as pharmaceutical entities or as simple dietary adjuncts to existing therapies.