Journal ArticleDOI
Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan.
TLDR
Overall this study showed that TCS decreased the synthesis of androgens followed by reduced sperm production in treated male rats which could be mediated by a decreased synthesis of LH and FSH thus involving hypothalamo-pituitary-gonadal axis.About:
This article is published in Reproductive Toxicology.The article was published on 2009-04-01. It has received 196 citations till now. The article focuses on the topics: Testosterone & Pregnenolone.read more
Citations
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Journal ArticleDOI
Triclosan: environmental exposure, toxicity and mechanisms of action
Andrea B. Dann,Alice Hontela +1 more
TL;DR: Concern has been raised over TCS's potential for endocrine disruption, as the antimicrobial has been shown to disrupt thyroid hormone homeostasis and possibly the reproductive axis, and there is strong evidence that aquatic species such as algae, invertebrates and certain types of fish are much more sensitive to TCS than mammals.
Journal ArticleDOI
Triclosan: Current Status, Occurrence, Environmental Risks and Bioaccumulation Potential
Gurpreet Singh Dhillon,Surinder Kaur,Rama Pulicharla,Satinder Kaur Brar,Maximiliano Cledón,Mausam P. Verma,Rao Y. Surampalli +6 more
TL;DR: Considering the worldwide application of personal care products containing TCS and inefficient removal and its toxic effects on aquatic organisms, the compound should be considered on the priority list of emerging contaminants and its utilization in all products should be regulated.
Journal ArticleDOI
Occurrence and toxicity of antimicrobial triclosan and by-products in the environment
Gilles Bedoux,Gilles Bedoux,Benoit Roig,Olivier Thomas,Virginie Dupont,Virginie Dupont,Barbara Le Bot +6 more
TL;DR: The excessive use of triclosan is suspected to increase the risk of emergence of TCS-resistant bacteria and the selection of resistant strains, as well as to produce cytotoxic, genot toxic, and endocrine disruptor effects.
Journal ArticleDOI
Exposure determinants of phthalates, parabens, bisphenol A and triclosan in Swedish mothers and their children.
Kristin Larsson,Karin Björklund,Brita Palm,Maria Wennberg,Lennart Kaj,Christian H. Lindh,Bo A. G. Jönsson,Marika Berglund +7 more
TL;DR: There were fairly good correlations of biomarker levels between the mothers and their children and the levels of high molecular weight phthalates and parabens were associated with consumption of certain foods and use of cosmetics and personal care products.
Journal ArticleDOI
Exposure to endocrine disrupting compounds via the food chain: Is packaging a relevant source?
TL;DR: The regulations and use of endocrine disrupting compounds (EDCs) in food packaging are reviewed and their presence within the context of new toxicology paradigms are discussed, with a focus on nonylphenol.
References
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Journal ArticleDOI
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
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Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
TL;DR: A new method of total RNA isolation by a single extraction with an acid guanidinium thiocyanate-phenol-chloroform mixture is described, providing a pure preparation of undegraded RNA in high yield and can be completed within 4 h.
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Molecular Biology of Steroid Hormone Synthesis
TL;DR: Five groups of steroid hormones are generally recognized according to their physiological behavior: mineralocorticoids, which instruct the renal tubules to retain sodium; glucocortics, which are named for their carbohydratemobilizing properties but have many other effects as well; estrogens, which induce female secondary sexual characteristics; progestins, which is essential for reproduction; and androgens, who induce male secondarySexual characteristics.
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StAR Protein and the Regulation of Steroid Hormone Biosynthesis
TL;DR: The tertiary structure of the START domain of a StAR homolog has been solved, and identification of a cholesterol-binding hydrophobic tunnel within this domain raises the possibility that StAR acts as aolesterol-shuttling protein.
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Pharmaceutical chemicals and endocrine disrupters in municipal wastewater in Tokyo and their removal during activated sludge treatment.
TL;DR: This is the first paper to report ubiquitous occurrence of crotamiton, a scabicide, in sewage and it is a promising molecular marker of sewage and secondary effluent.
Related Papers (5)
Triclosan: environmental exposure, toxicity and mechanisms of action
Andrea B. Dann,Alice Hontela +1 more