Another set of responses and correlated responses to selection on age at reproduction in Drosophila melanogaster.
TLDR
Breeding from older adults resulted in an evolutionary increase in survival but, contrary to all previous studies using this method, in no increase in late–life fertility, confirming the importance of pleiotropy in the evolution of ageing.Citations
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Why do we age
TL;DR: The evolutionary theory of ageing explains why ageing occurs and helps to clarify how the genome shapes the ageing process, thereby aiding the study of the genetic factors that influence longevity and age-associated diseases.
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The Physiology of Life History Trade-Offs in Animals
TL;DR: A review of life historyTrade-offs discusses conceptual issues associated with physiological aspects of trade-offs, and it describes recent advances on this topic.
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Human longevity at the cost of reproductive success.
TL;DR: Female longevity was negatively correlated with number of progeny and positively correlated with age at first childbirth, and the findings show that human life histories involve a trade-off between longevity and reproduction.
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Invited review: Theories of aging.
TL;DR: The presence of several trajectories of the life span, from incidence of disease and disability to absence of pathology and persistence of function, suggest that it is possible to experimentally prolong functional plasticity and life span.
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Mechanisms of ageing: public or private?
Linda Partridge,David Gems +1 more
TL;DR: Evidence is mounting that modulators of the rate of ageing are conserved over large evolutionary distances, and this conservation might stem from mechanisms that match reproductive rate to nutrient supply.
References
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Pleiotropy, natural selection, and the evolution of senescence
TL;DR: August Weismann's theory is subject to a number of criticisms, the most forceful of which are: 1) The fallacy of identifying senescence with mechanical wear, 2) the extreme rarity, in natural populations, of individuals that would be old enough to die of the postulated death-mechanism, 3) the failure of several decades of gerontological research to uncover any deathmechanisms, and 4) the difficulties involved in visualizing how such a feature could be produced
Journal Article
Pleiotropy, Natural Selection, and the Evolution of Senescence
TL;DR: A new individual entering a population may be said to have a reproductive probability distribution as discussed by the authors, where the reproductive probability is zero from zygote to reproductive maturity, i.e., the individual will have no reproductive capability from birth to maturity.
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Natural Selection, the Costs of Reproduction, and a Refinement of Lack's Principle
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The moulding of senescence by natural selection.
TL;DR: A basis for the theory that senescence is an inevitable outcome of evolution is established and the model shows that higher fertility will be a primary factor leading to the evolution of higher rates ofsenescence unless the resulting extra mortality is confined to the immature period.