Journal ArticleDOI
Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita.
TLDR
The result suggests that cirsilineol, 6-methoxytricin and apigenin are the major active components in Artemisia vestita.About:
This article is published in Journal of Ethnopharmacology.The article was published on 2008-10-30. It has received 136 citations till now. The article focuses on the topics: Cirsilineol & Flavones.read more
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Effects of Flavonoids and other Polyphenols on Inflammation
Raquel González,Isabel Ballester,Rocío López-Posadas,María Dolores Suárez,Antonio Zarzuelo,Olga Martínez-Augustin,F. Sánchez de Medina +6 more
TL;DR: There is substantial consistency in the effects of these compounds despite considerable structural variations, and at present there is a gap in knowledge of in vitro and in vivo effects, although the pharmacokinetics of flavonoids has advanced considerably in the last decade.
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Recovery, concentration and purification of phenolic compounds by adsorption: A review
María Luisa Soto,Andrés Moure,Andrés Moure,Herminia Domínguez,Herminia Domínguez,Juan Carlos Parajó,Juan Carlos Parajó +6 more
TL;DR: In this paper, the equilibrium and kinetic principles of adsorption and desorption were reviewed for solutions containing phenolic compounds, as well as their application in food-oriented processes, including detoxification of fermentation media, color removal and purification of sugar solutions and microbial metabolites.
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The genus Artemisia: a comprehensive review.
Kundan Singh Bora,Anupam Sharma +1 more
TL;DR: Various species of Artemisia seems to hold great potential for in-depth investigation for various biological activities, especially their effects on the central nervous and cardiovascular systems.
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Composition and anti-oxidant, anti-cancer and anti-inflammatory activities of Artemisia herba-alba, Ruta chalpensis L. and Peganum harmala L.
TL;DR: Findings demonstrate the remarkable potential of these plants as valuable source of antioxidants with exhibit original and interesting anti-inflammatory and anticancer capacities.
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Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2-mediated PI3K/Akt/mTOR signaling pathway.
Lijun He,Yuanyuan Wu,Lei Lin,Jieqiong Wang,Yougen Wu,Yihua Chen,Zhengfang Yi,Mingyao Liu,Mingyao Liu,Xiufeng Pang +9 more
TL;DR: Results indicate that hispidulin targets the VEGF receptor 2‐mediated PI3K/Akt/mTOR signaling pathway in endothelial cells, leading to the suppression of pancreatic tumor growth and angiogenesis.
References
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Early molecular events in the induction phase of contact sensitivity
Alexander Enk,Stephen I. Katz +1 more
TL;DR: It is demonstrated that Langerhans cell-derived and certain keratinocyte-derived cytokine mRNAs are selectively upregulated by allergens in the very early afferent phase of contact sensitivity.
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Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae).
TL;DR: The main mode of action of the Tripterygium extracts and triptolide is the inhibition of expression of proinflammatory genes such as those for interleukin-2, inducible nitric oxide synthase, tumor necrosis factor-alpha, cyclooxygenase-2 and interferon-gamma.
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Biologically Active Substances from the Genus Artemisia
TL;DR: This review summarizes mainly the biological results obtained in the past decade from Artemisia species, which are frequently utilized for the treatment of diseases such as malaria, hepatitis, cancer, inflammation, and infections by fungi, bacteria, and viruses.
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Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum sanctum Linn.
TL;DR: The results support traditional uses of O. sanctum and identify the compounds responsible, and Eugenol, a major component of the volatile oil, and compounds 1, 3, 4, and 6 demonstrated good antioxidant activity at 10-microM concentrations.
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Immunosuppressive drugs: the first 50 years and a glance forward.
TL;DR: A promising future application of immunosuppressive drugs is their use in a regime to induce tolerance to allografts, and the induction of apoptosis of clones of responding T-lymphocytes, is discussed.