Journal ArticleDOI
Aptamer-conjugated gold nanoparticles for targeted paclitaxel delivery and photothermal therapy in breast cancer
TLDR
In this article , a photothermal therapy (PTT) based multifunctional drug delivery platform was proposed for breast cancer. And the authors evaluated the synergistic effect of PTX/[email protected] was evaluated in vitro cell cytotoxicity experiments on MUC1-positive and MUC 1-negative breast cancer cells.About:
This article is published in Journal of Drug Delivery Science and Technology.The article was published on 2022-01-01. It has received 12 citations till now. The article focuses on the topics: Photothermal therapy & Paclitaxel.read more
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Recent advances and trends in nanoparticles based photothermal and photodynamic therapy
Ayuob Aghanejad,Soodabeh Davaran +1 more
TL;DR: In this paper , the basic principles of photodynamic therapy (PDT) and photothermal therapy (PTT) with their strengths and limitations to treat cancers are discussed. And the authors also discuss light-based nanoparticles and their PTT and PDT applications in the preclinical and clinical translation.
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Green nanotechnology—An innovative pathway towards biocompatible and medically relevant gold nanoparticles
Velaphi C. Thipe,Alice Raphael Karikachery,Pınar Çakılkaya,Umer Farooq,H. Genedy,Norraseth Kaeokhamloed,Dieu Hien Phan,Refaya Rezwan,Gozde Tezcan,Emilie Roger,Kattesh V. Katti +10 more
TL;DR: In this article , the authors provide details on reliable synthetic pathways towards biocompatible and medically relevant gold and radioactive gold nanoparticles, and discuss the role of gold in nanomedicine.
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Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy
Sunil Kumar,Monu Kumar Shukla,Abhishek Sharma,Gururaj Kudur Jayaprakash,Rajiv K. Tonk,Dinesh Kumar Chellappan,Sachin Kumar Singh,Kamal Dua,Faheem Ahmed,Sanjib Bhattacharyya,Deepak Kumar +10 more
TL;DR: A review of the potential of plant and metal-based nano-materials with their effects on size and shape has been discussed in this article , along with their more effective usage in cancer diagnosis and treatment.
Journal ArticleDOI
Aptamers as Smart Ligands for Targeted Drug Delivery in Cancer Therapy
TL;DR: In this article , the authors reviewed the application of aptamers as smart ligands for targeted drug delivery in cancer therapy and focused on the aptamer-conjugated nanocarriers, aptamer targeting strategy for tumor microenvironment (TME), and aptamer that are specified to crucial cancer biomarkers for targeted drugs delivery.
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AS1411 conjugated magnetic‐based poly <i>N</i> ‐isopropyl acrylamide nanoparticles for delivery of erlotinib to prostate cancer cells
TL;DR: In this paper , a magnetic pH-dependent and nucleolin receptor-targeted nano-drug delivery system consisting of synthesized superparamagnetic iron oxide nanoparticles (SPIONs) and poly N-isopropyl acrylamide (PNIPAM) with aptamer AS1411 to deliver the erlotinib (ERL) to prostate cancer (PC) cells.
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Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles
TL;DR: It is found that the malignant cells require less than half the laser energy to be killed than the benign cells after incubation with anti-EGFR antibody conjugated Au nanoparticles, offering a novel class of selective photothermal agents using a CW laser at low powers.
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Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications
TL;DR: A State-of-the-art use of PEG in therapeutic applications, its clinical status and commercial use is summarized, and toxicities related to different PEG grades and related impurities are discussed in this review.
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Gold Nanoparticles for Photothermal Cancer Therapy.
TL;DR: A quick review of the structure, applications, recent advancements, and potential future directions for the utilization of gold nanoparticles in cancer therapeutics is given.
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Autophagy and multidrug resistance in cancer
Ying-Jie Li,Yu-He Lei,Nan Yao,Chen-Ran Wang,Nan Hu,Wen-Cai Ye,Dong-Mei Zhang,Zhe-Sheng Chen,Zhe-Sheng Chen +8 more
TL;DR: In this paper, the authors summarize advanced studies of autophagy in multidrug resistance (MDR) tumors, including the variable role of auto-gathering in MDR cancer cells.
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The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy.
TL;DR: 24 research articles and reviews discussing different aspects of the EPR effect and cancer nanomedicine are collected, together providing a comprehensive and complete overview of the current state-of-the-art and future directions in tumor-targeted drug delivery.