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Journal ArticleDOI

Arterial pressure regulation: Overriding dominance of the kidneys in long-term regulation and in hypertension☆

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TLDR
All long-term arterial pressure regulation must involve the balance between intake and output of water and salt and almost invariably involves the kidneys.
About
This article is published in The American Journal of Medicine.The article was published on 1972-05-01. It has received 1048 citations till now. The article focuses on the topics: Blood pressure & Kidney metabolism.

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Citations
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Gender Differences in the Regulation of Blood Pressure

TL;DR: Findings in animal studies show that there is a blunting of the pressure-natriuresis relationship in male spontaneously hypertensive rats and in ovariectomized female spontaneously hypertension rats treated chronically with testosterone, suggesting that the loss of estrogens may be the only component involved in the higher blood pressure in women after menopause.
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Blood pressure control--special role of the kidneys and body fluids.

TL;DR: The arterial pressure of the adult human rarely deviates from normal by more than 10 to 15 percent during each day, and to achieve such constancy, the body has a network of pressure control systems based on neural receptors that respond within seconds to help correct any abnormal pressure.
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Evolving importance of kidney disease: from subspecialty to global health burden

TL;DR: Strong, graded, and consistent associations exist between clinical prognosis and two hallmarks of chronic kidney disease: reduced glomerular filtration rate and increased urinary albumin excretion.
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Role of the Baroreceptor Reflex in Daily Control of Arterial Blood Pressure and Other Variables in Dogs

TL;DR: The primary function of the baroreceptor reflex is not to set the chronic level of arterial blood pressure but, instead, to minimize variations in systemic arterialBlood pressure, whether these variations are caused by postural changes of the animal, excitement, diurnal rhythm, or even spontaneous fluctuations of unknown origin.
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The Cardiovascular-Behavioral Interaction—As It Appears Today

TL;DR: Emerging evidence suggests that with passive coping such as classical aversive conditioning, the heart is more under vagal control which is directionally linked with somatic activity, while blood pressure is more dominated by vascular processes.
References
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Reflexogenic Areas of the Cardiovascular System

TL;DR: Experiments done between 1877 and 1926 showed that a rise of blood pressure in the carotid-cephalic circulation induces bradycardia and a fall of the systemic arterial pressure, while a drop in the vehicle pressure provokes acceleration of the heart rate and a rise in the systemicarterial pressure.
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Hypotensive Agents and Pressor Substances: The Effect of Epinephrine, Norepinephrine, Angiotensin II, and Others on the Secretory Rate of Aldosterone in Man

TL;DR: The results suggest that aldosterone may regulate salt balance and blood pressure by its interaction with pressor substances such as angiotensin.
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The Elastic Symmetry of Arterial Segments in Dogs

TL;DR: It was concluded that the vessel has elastic properties that are nearly symmetrical about the planes perpendicular to principal stresses under physiologic loading, i.e., the vessel may be treated as a cylindrically orthotropic tube.
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