Journal ArticleDOI
Articular Cartilage Reconstruction with TGF-β1-Simulating Self-Assembling Peptide Hydrogel-Based Composite Scaffold.
Wei Ye,Zhen Yang,Fuyang Cao,Hao Li,Tianyuan Zhao,Huan Zhang,Zhe Zhang,Shuhui Yang,Jinjin Zhu,Zhu Liu,Jingchuan Zheng,Huiying Liu,Guowu Ma,Quanyi Guo,Xiumei Wang +14 more
TLDR
In this article , the TGF-β1-simulating peptide LIANAK (CM) was connected with the self-assembling peptide Ac-(RADA)4-GG-LIANAK-CONH2 (RAD-CM).About:
This article is published in Acta Biomaterialia.The article was published on 2022-05-01. It has received 15 citations till now. The article focuses on the topics: Medicine & Chondrogenesis.read more
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Peptide-Based Hydrogels: New Materials for Biosensing and Biomedical Applications
TL;DR: An updated report on the advancement of peptide-based hydrogels research activity in recent years in the field of anticancer drug delivery, antimicrobial and wound healing materials, 3D bioprinting and tissue engineering, and vaccines is presented.
Journal ArticleDOI
Biofabrication of the osteochondral unit and its applications: Current and future directions for 3D bioprinting
Patricia Santos-Beato,Swati Midha,Andrew A. Pitsillides,Aline F. Miller,Ryo Torii,Deepak M. Kalaskar +5 more
TL;DR: A review of 3D bioprinted osteochondral tissues can be found in this paper , focusing on the most used bioinks, chosen cell types and growth factors, as well as further illustrating limitations and improvements that could be performed explicitly for disease modelling.
Journal ArticleDOI
Research progress of self-assembling peptide hydrogels in repairing cartilage defects
TL;DR: The purpose of this review is to sum up the composition, injury characteristics, and treatments of articular cartilage, as well as the action of SAPHs in repairing articularcartilage damage.
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Progress of Wnt Signaling Pathway in Osteoporosis
TL;DR: Wang et al. as mentioned in this paper analyzed the mechanisms of Wnt proteins, β-catenin, and signaling molecules in the process of signal transduction and summarized the relationship between the Wnt signaling pathway and bone-related cells.
Journal ArticleDOI
Advances in Peptide-Based Hydrogel for Tissue Engineering
TL;DR: The peptide-based hydrogels have attracted considerable interest in tissue engineering because they mimic tissue formation conditions by providing a three-dimensional environment and a high water content as mentioned in this paper .
References
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Journal ArticleDOI
Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane.
TL;DR: This work has shown that a 16-residue peptide has a characteristic beta-sheet circular dichroism spectrum in water and spontaneously assembles to form a macroscopic membrane, which may be a model for studying the insoluble peptides found in certain neurological disorders.
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TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease
TL;DR: This review summarizes the recent advances in the understanding of TGF-β/BMP signaling in osteoblast differentiation, chondrocyte differentiation, skeletal development, cartilage formation, bone formation,Bone homeostasis, and related human bone diseases caused by the disruption of T GF-β / BMP signaling.
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Repair and tissue engineering techniques for articular cartilage
Eleftherios Makris,Andreas H. Gomoll,Konstantinos N. Malizos,Jerry C. Hu,Kyriacos A. Athanasiou +4 more
TL;DR: Current, widely used clinical repair techniques for resurfacing articular cartilage defects and a developmental pipeline of acellular and cellular regenerative products and techniques that could revolutionize joint care over the next decade by promoting the development of functional articular Cartilage are described.
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Unlike Bone, Cartilage Regeneration Remains Elusive
TL;DR: Bone-regeneration successes are used to highlight cartilage- Regeneration challenges: such as selecting appropriate cell sources and scaffolds, creating biomechanically suitable tissues, and integrating to native tissue.
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Injectable hydrogels for cartilage and bone tissue engineering.
Mei Liu,Xin Zeng,Chao Ma,Huan Yi,Zeeshan Ali,Zeeshan Ali,Xianbo Mou,Song Li,Yan Deng,Yan Deng,Nongyue He,Nongyue He +11 more
TL;DR: The selection of appropriate biomaterials and fabrication methods to prepare novel injectable hydrogels for cartilage and bone tissue engineering are described and the biology of Cartilage and the bony ECM is summarized.