Injectable hydrogels for cartilage and bone tissue engineering.
Mei Liu,Xin Zeng,Chao Ma,Huan Yi,Zeeshan Ali,Zeeshan Ali,Xianbo Mou,Song Li,Yan Deng,Yan Deng,Nongyue He,Nongyue He +11 more
TLDR
The selection of appropriate biomaterials and fabrication methods to prepare novel injectable hydrogels for cartilage and bone tissue engineering are described and the biology of Cartilage and the bony ECM is summarized.Abstract:
Tissue engineering has become a promising strategy for repairing damaged cartilage and bone tissue Among the scaffolds for tissue-engineering applications, injectable hydrogels have demonstrated great potential for use as three-dimensional cell culture scaffolds in cartilage and bone tissue engineering, owing to their high water content, similarity to the natural extracellular matrix (ECM), porous framework for cell transplantation and proliferation, minimal invasive properties, and ability to match irregular defects In this review, we describe the selection of appropriate biomaterials and fabrication methods to prepare novel injectable hydrogels for cartilage and bone tissue engineering In addition, the biology of cartilage and the bony ECM is also summarized Finally, future perspectives for injectable hydrogels in cartilage and bone tissue engineering are discussedread more
Citations
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Mesenchymal Stem Cells for Regenerative Medicine.
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Cellulose nanocrystals and cellulose nanofibrils based hydrogels for biomedical applications.
Haishun Du,Haishun Du,Haishun Du,Wei Liu,Miaomiao Zhang,Chuanling Si,Chuanling Si,Xinyu Zhang,Bin Li +8 more
TL;DR: This work demonstrated that the CNCs and CNFs based hydrogels have great promise in a wide range of biomedical applications in the future.
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3D printing of hydrogels: Rational design strategies and emerging biomedical applications
TL;DR: A review of hydrogel-based biomaterial inks and bioinks for 3D printing can be found in this paper, where the authors provide a comprehensive overview and discussion of the tailorability of material, mechanical, physical, chemical and biological properties.
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Printability and Shape Fidelity of Bioinks in 3D Bioprinting.
Andrea Schwab,Riccardo Levato,Matteo D'Este,Susanna Piluso,Susanna Piluso,David Eglin,Jos Malda +6 more
TL;DR: The physicochemical parameters influencing shape fidelity are discussed, together with their importance in establishing new models, predictive tools and printing methods that are deemed instrumental for the design of next-generation bioinks, and for reproducible comparison of their structural performance.
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Advances in crosslinking strategies of biomedical hydrogels
TL;DR: The commonly used crosslinking method for hydrogel synthesis involving physical and chemical crosslinks is presented and their current progress and future perspectives are summarized.
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