Journal ArticleDOI
Artificial membranes as carriers for the immobilization of biocatalysts
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TLDR
Artificial membranes, due to their interesting properties (high surface area per unit volume, possibility to combine separation with chemical reaction etc).About:
This article is published in Enzyme and Microbial Technology.The article was published on 1986-08-01. It has received 82 citations till now.read more
Citations
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Journal ArticleDOI
Polyethyleneimine in immobilization of biocatalysts.
TL;DR: Polyethyleneimine (PEI), with the highest concentration of amino groups, has found acceptance as a carrier in a number of industrial immobilized biosystems and is claimed to highlight the potential of PEI.
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Enzymatic membrane bioreactors and their applications
TL;DR: The basic concepts, advantages, problems, and applications of enzymatic membrane reactors are reviewed in this article and a broad classification of this type of reactor is proposed based on the type of contact between enzyme and substrates that occurs in these devices.
Journal ArticleDOI
Fundamentals of immobilised yeast cells for continuous beer fermentation: a review
TL;DR: The latest studies on immobilised cell carriers, viability, vitality, mass transfer characteristics and bioreactor design indicate that an industrial scale immobilisation cell system for primary beer fermentation may soon be a reality in the modern brewery.
Journal ArticleDOI
Membranes and bioreactors: a technical challenge in biotechnology.
TL;DR: The advantages and limitations of using membrane bioreactors for entrapping whole cells and enzymes, including single, laminated and microporous, for the conversion of optically active enantiomers are reviewed.
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A capillary membrane bioreactor using immobilized polyphenol oxidase for the removal of phenols from industrial effluents
W Edwards,R Bownes,W.D. Leukes,E. P. Jacobs,Ronald Douglas Sanderson,Peter Dale Rose,Stephanie G. Burton +6 more
TL;DR: Almost complete removal of the colored quinones and associated polymers from the permeate was observed and this membrane allows greater flux and was shown to facilitate high efficiency in removal of reaction products from the reactor.
References
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A mild method of general use for covalent coupling of enzymes to chemically activated collagen films
TL;DR: Films of highly polymerized collagen, prepared in industrial conditions, were chosen for surface covalent binding of enzymes because of their insolubility, mechanical resistance, proteic nature, hydrophilic properties and for their abundance in chemically activable COOH.
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Hollow-fiber membrane bioreactors using immobilized E. coli for protein synthesis.
Douglas S. Inloes,William J. Smith,Dean P. Taylor,Stanley N. Cohen,Alan S. Michaels,Channing R. Robertson +5 more
TL;DR: Reactor productivity was dependent on the number of cells in the reactor, suggesting that reactor performance was kinetically controlled and not mass transport limited, and hollow‐fiber bioreactor was 100 times more productive than the shaker‐flask culture on a reactor‐volume basis.
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The immobilization of enzymes on nylon structures and their use in automated analysis.
D. J. Inman,W. E. Hornby +1 more
TL;DR: The efficiencies of the three immobilized enzyme structures as reagents for the automated determination of their substrates were compared and an improved process is described for the immobilization of glucose oxidase and urease on the inside surface of partially hydrolysed nylon tube.
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Development of a hollow‐fiber system for large‐scale culture of mammalian cells
TL;DR: A flat‐bed hollow‐fiber cell culture system has been developed which maximizes the utilization of the large fiber surface while diminishing significantly the problems inherent in a cartridge‐type reactor.
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Enzymatic hydrolysis of sodium-hydroxide-pretreated sallow in an ultrafiltration membrane reactor.
TL;DR: Product inhibition could be eliminated by continuous removal of products through the ultrafiltration membrane, thus retaining the macromolecular substrate and enzymes, and the degree of conversion was improved from 40% in a batch hydrolysis to 95% (within 20 h), and the initial hydrolytic rate was increased up to seven times.