Journal ArticleDOI
Assessment of interactions between four proteins and benzothiazole derivatives by DSC and CD
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TLDR
In this article, the thermal denaturation of ovalbumin, lysozyme, myoglobin and fibrinogen at different BTS concentrations were investigated using differential scanning calorimetry (DSC) and circular dichroism (CD) spectroscopy.About:
This article is published in The Journal of Chemical Thermodynamics.The article was published on 2011-03-01. It has received 22 citations till now. The article focuses on the topics: Denaturation (biochemistry) & Circular dichroism.read more
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Benzotriazoles and benzothiazoles in human urine from several countries: A perspective on occurrence, biotransformation, and human exposure
TL;DR: Based on the concentrations and detection rates of several BTR and BTH derivatives in urine, possible metabolic transformation pathways of these compounds were presented and human exposure doses calculated.
Journal ArticleDOI
The influence of nanostructured materials on biointerfacial interactions.
TL;DR: This work highlights some of the key technologies used for fabrication of nanostructured materials, examines how nanostructure materials influence the behavior of proteins and cells at surfaces and provides details of important analytical techniques used in this context.
Journal ArticleDOI
Determination of Benzotriazoles and Benzothiazoles in Human Urine by Liquid Chromatography-Tandem Mass Spectrometry
Alexandros G. Asimakopoulos,Anna A. Bletsou,Anna A. Bletsou,Qian Wu,Nikolaos S. Thomaidis,Kurunthachalam Kannan +5 more
TL;DR: This is the first study on the occurrence of 10 BTR and BTH compounds in human urine and a liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI(+)MS/MS) method was developed for simultaneous determination.
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Application of the SOS/umu test and high-content in vitro micronucleus test to determine genotoxicity and cytotoxicity of nine benzothiazoles
TL;DR: Through quantitative structure–activity relationship analysis, two structure alerts for chemical genotoxicity, including heterocyclic amine and hacceptor‐path3‐hacceptor are present in ABT and OHBT respectively; however, the underlying mechanisms still need further evaluation.
Journal ArticleDOI
Fibrinogen: a journey into biotechnology
TL;DR: The bulk properties of the molecule as well as its supramolecular assembly with different ligands by using different techniques and theoretical models and its main application in biotechnology are described.
References
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Journal ArticleDOI
DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data.
Lee Whitmore,Bonnie A. Wallace +1 more
TL;DR: The DICHROWEB web server enables on-line analyses of circular dichroism (CD) spectroscopic data, providing calculated secondary structure content and graphical analyses comparing calculated structures and experimental data.
Book
Interactions of Surfactants with Polymers and Proteins
TL;DR: The physical chemistry of individual components (surfactants, polymers, and proteins) is discussed, and extensive coverage of interactions of surfactants with uncharged, oppositely charged, and hydrophobe modified polymers is provided as discussed by the authors.
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Structure of myoglobin refined at 2-0 A resolution. I. Crystallographic refinement of metmyoglobin from sperm whale.
TL;DR: The structure of sperm whale metmyoglobin has been refined using new intensity data to 2·0 A collected on a four-circle diffractometer starting with the original phase angles determined by isomorphous replacement with heavy atoms.
Journal ArticleDOI
Biochemical Applications of Differential Scanning Calorimetry
TL;DR: Differential scanning calorimetry (DSC) and the closely related differential thermal analysis (DTA) have been widely employed during the last several decades in the thermodynamic study of processes that are initiated by either an increase or a decrease in temperature as discussed by the authors.