Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis.
Kunihiro Matsushita,Marije van der Velde,Brad C. Astor,Mark Woodward,Andrew S. Levey,Paul E. de Jong,Josef Coresh,Ron T. Gansevoort,Meguid El-Nahas,Kai-Uwe Eckardt,Bertram L. Kasiske,Marcello Tonelli,Brenda R. Hemmelgarn,Yaping Wang,Robert C. Atkins,Kevan R. Polkinghorne,Steven J. Chadban,Anoop Shankar,Ronald Klein,Barbara E.K. Klein,Haiyan Wang,Fang Wang,Luxia Zhang,Lisheng Liu,Michael G. Shlipak,Mark J. Sarnak,Ronit Katz,Linda Fried,Tazeen H. Jafar,M. Mazharul Islam,Juanita Hatcher,Neil R Poulter,Nish Chaturvedi,Dietrich Rothenbacher,Hermann Brenner,Elke Raum,Wolfgang Koenig,Caroline S. Fox,Shih-Jen Hwang,James B. Meigs,Massimo Cirillo,Stein Hallan,Stian Lydersen,Jostein Holmen,Paul Roderick,Dorothea Nitsch,Astrid E. Fletcher,Christopher J. Bulpitt,Takayoshi Ohkubo,Hirohito Metoki,Masaaki Nakayama,Masahiro Kikuya,Yutaka Imai,Simerjot K. Jassal,Elizabeth Barrett-Connor,Jaclyn Bergstrom,David G. Warnock,Paul Muntner,Suzanne E. Judd,William M. McClellan,Mary Cushman,George Howard,Leslie A. McClure,Sun Ha Jee,Heejin Kimm,Ji Eun Yun,Chi Pang Wen,Sung Feng Wen,Chwen Keng Tsao,Min Kuang Tsai,Johan Ärnlöv,Priscilla Auguste,Kasper Veldhuis,Laura Camarata,Beverly Thomas,Tom Manley +75 more
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TLDR
In this article, a meta-analysis of general population cohorts was conducted to assess the independent and combined associations of estimated glomerular filtration rate (eGFR) and albuminuria with mortality.About:
This article is published in The Lancet.The article was published on 2010-06-12 and is currently open access. It has received 3087 citations till now. The article focuses on the topics: Albuminuria & Risk of mortality.read more
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Mendelian Randomization as an Approach to Assess Causality Using Observational Data
TL;DR: Special issues in nephrology are discussed, such as inverse risk factor associations in advanced disease, and opportunities to design Mendelian randomization studies around kidney function and disease are outlined.
Journal ArticleDOI
Systematic review: blood pressure target in chronic kidney disease and proteinuria as an effect modifier.
TL;DR: Comparing lower versus higher blood pressure targets in adult patients with CKD and focusing on proteinuria as an effect modifier shows available evidence is inconclusive but does not prove that a blood pressure target of less than 130/80 mm Hg improves clinical outcomes more than a target of more than 140/90mm Hg.
KDOQI Commentary KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for the Evaluation and Management of CKD
Lesley A. Inker,Brad C. Astor,Chester H. Fox,Tamara Isakova,James P. Lash,Carmen A. Peralta,Manjula Kurella Tamura,Harold I. Feldman +7 more
TL;DR: A work group agreed with most of the recommendations contained in the KDIGO guidelines, particularly the recommendations regarding the definition and classification of CKD, however, there were some concerns about incorporating the cause of disease into CKD classification.
Journal ArticleDOI
Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial
David Z.I. Cherney,David Z.I. Cherney,Bernard Zinman,Silvio E. Inzucchi,Audrey Koitka-Weber,Michaela Mattheus,Maximilian von Eynatten,Christoph Wanner +7 more
TL;DR: In this article, the short-term and long-term effects of empagliflozin on albuminuria in patients with type 2 diabetes and established cardiovascular disease were investigated.
Journal ArticleDOI
Clinical Practice Guideline for the Management of Chronic Kidney Disease in Patients Infected With HIV: 2014 Update by the HIV Medicine Association of the Infectious Diseases Society of America
Gregory M. Lucas,Michael W. Ross,Peter G. Stock,Michael G. Shlipak,Christina M. Wyatt,Samir K. Gupta,Mohamed G. Atta,Kara Wools-Kaloustian,Paul A. Pham,Leslie A. Bruggeman,Jeffrey L. Lennox,Patricio E. Ray,Robert C. Kalayjian +12 more
TL;DR: IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances.
References
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Journal ArticleDOI
A New Equation to Estimate Glomerular Filtration Rate
Andrew S. Levey,Lesley A. Stevens,Christopher H. Schmid,Yaping (Lucy) Zhang,Alejandro F. Castro,Harold I. Feldman,John W. Kusek,Paul W. Eggers,Frederick Van Lente,Tom Greene,Josef Coresh +10 more
TL;DR: The CKD-EPI creatinine equation is more accurate than the Modification of Diet in Renal Disease Study equation and could replace it for routine clinical use.
Journal Article
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Scott M. Grundy,Diane M. Becker,Luther T. Clark,Richard S. Cooper,Margo A. Denke,James P. Howard,Donald B. Hunninghake,D. Roger Illingworth,Russell V. Luepker,Patrick E. McBride,James M. McKenney,Richard C. Pasternak,Neil J. Stone,Linda Van Horn +13 more
Journal Article
K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification
Andrew S. Levey,Josef Coresh,Kline Bolton,Bruce Culleton,Kathy Schiro Harvey,T. Alp Ikizler,Cynda Ann Johnson,Annamaria T. Kausz,Paul L. Kimmel,John W. Kusek,Adeera Levin,Kenneth L. Minaker,Robert Nelson,Helmut G. Rennke,Michael Steffes,Beth Witten,Ronald J. Hogg,Susan Furth,Kevin V. Lemley,Ronald J. Portman,George Schwartz,Joseph Lau,Ethan M Balk,Ronald D. Perrone,Tauqeer Karim,Lara Rayan,Inas Al-Massry,Priscilla Chew,Brad C. Astor,Deirdre De Vine,Garabed Eknoyan,Nathan W. Levin,Sally Burrows-Hudson,William F. Keane,Alan S. Kliger,Derrick Latos,Donna Mapes,Edith Oberley,Kerry Willis,George R. Bailie,Gavin J. Becker,Jerrilynn Burrowes,David Churchill,Allan J. Collins,William Couser,Dick DeZeeuw,Alan Garber,Thomas Golper,Frank A. Gotch,Antonio M. Gotto,Joel W. Greer,Richard H. Grimm,Ramon G. Hannah,Jaime Herrera Acosta,Ronald J. Hogg,Lawrence G. Hunsicker,Michael J. Klag,Saulo Klahr,Caya Lewis,Edmund G. Lowrie,Arthur J. Matas,Sally McCulloch,Maureen Michael,Joseph V. Nally,John M. Newmann,Allen R. Nissenson,Keith Norris,William F. Owen,Thakor G. Patel,Glenda Payne,Rosa A. Rivera-Mizzoni,David A. Smith,Robert A. Star,Theodore Steinman,Fernando Valderrábano,John Walls,Jean Pierre Wauters,Nanette Wenger,Josephine P. Briggs +78 more
TL;DR: In the early 1990s, the National Kidney Foundation (K/DOQI) developed a set of clinical practice guidelines to define chronic kidney disease and to classify stages in the progression of kidney disease.
Journal ArticleDOI
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
TL;DR: The longitudinal glomerular filtration rate was estimated among 1,120,295 adults within a large, integrated system of health care delivery in whom serum creatinine had been measured between 1996 and 2000 and who had not undergone dialysis or kidney transplantation.
Journal ArticleDOI
Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate.
Andrew S. Levey,Josef Coresh,Tom Greene,Lesley A. Stevens,Yaping (Lucy) Zhang,Stephen Hendriksen,John W. Kusek,Frederick Van Lente +7 more
TL;DR: The MDRD Study equation has now been reexpressed for use with a standardized serum creatinine assay, allowing GFR estimates to be reported in clinical practice by using standardized serumcreatinine and overcoming this limitation to the current use of GFR estimating equations.
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