Journal ArticleDOI
Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial
Frank Thies,Jennifer M C Garry,Parveen Yaqoob,Kittipan Rerkasem,Jennifer A. Williams,Cliff Shearman,Patrick J. Gallagher,Philip C. Calder,Robert F. Grimble +8 more
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TLDR
Stability of plaques could explain reductions in non-fatal and fatal cardiovascular events associated with increased n-3 PUFA intake, and inducing changes that can enhance stability of atherosclerotic plaques.About:
This article is published in The Lancet.The article was published on 2003-02-08. It has received 751 citations till now. The article focuses on the topics: Polyunsaturated fatty acid & Fish oil.read more
Citations
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Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis
Mitsuhiro Yokoyama,Hideki Origasa,Masunori Matsuzaki,Yuji Matsuzawa,Yasushi Saito,Yuichi Ishikawa,Shinichi Oikawa,Jun Sasaki,Hitoshi Hishida,Hiroshige Itakura,Toru Kita,Akira Kitabatake,Noriaki Nakaya,Toshiie Sakata,Kazuyuki Shimada,Kunio Shirato +15 more
TL;DR: Testing the hypothesis that long-term use of eicosapentaenoic acid (EPA) is effective for prevention of major coronary events in hypercholesterolaemic patients in Japan who consume a large amount of fish found it to be a promising treatment.
Journal ArticleDOI
The Omega-3 Index: a new risk factor for death from coronary heart disease?
TL;DR: In this article, the Omega-3 Index was proposed as a new risk factor for death from coronary heart disease (CHD) and the relationship between this putative marker and risk for CHD death, especially sudden cardiac death (SCD), was evaluated in several published primary and secondary prevention studies.
Journal ArticleDOI
N-3 fatty acids and cardiovascular events after myocardial infarction.
TL;DR: Low-dose supplementation with EPA-DHA or ALA did not significantly reduce the rate of major cardiovascular events among patients who had had a myocardial infarction and who were receiving state-of-the-art antihypertensive, antithrombotic, and lipid-modifying therapy.
Journal ArticleDOI
Omega-3 Fatty Acids and Inflammatory Processes
TL;DR: The anti-inflammatory effects of marine n-3 PUFAs suggest that they may be useful as therapeutic agents in disorders with an inflammatory component.
References
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Journal ArticleDOI
Lessons From Sudden Coronary Death A Comprehensive Morphological Classification Scheme for Atherosclerotic Lesions
TL;DR: This review will reconsider the current paradigm for understanding the critical, final steps in the progression of atherosclerotic lesions, and devise a simpler classification scheme that is consistent with the AHA categories but is easier to use, able to deal with a wide array of morphological variations, and not overly burdened by mechanistic implications.
Journal ArticleDOI
Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial
TL;DR: Dietary supplementation with n-3 PUFA led to a clinically important and statistically significant benefit and vitamin E had no benefit and its effects on fatal cardiovascular events require further exploration.
Journal ArticleDOI
A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis A Report From the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association
H. C. Stary,A. B. Chandler,R. E. Dinsmore,Valentin Fuster,S. Glagov,William Insull,M. E. Rosenfeld,C. J. Schwartz,W. D. Wagner,R. W. Wissler +9 more
TL;DR: The histological classification of human atherosclerotic lesions found in the second part of this report led to the earlier definitions of precursor lesions, and the appearance of lesions noted in clinical imaging studies with histological lesion types and corresponding clinical syndromes was attempted.
Journal ArticleDOI
Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (dart)
Michael Leslie Burr,J. F. Gilbert,R. M. Holliday,Peter Creighton Elwood,Ann M. Fehily,S. Rogers,P. M. Sweetnam,N. M. Deadman +7 more
TL;DR: A modest intake of fatty fish (two or three portions per week) may reduce mortality in men who have recovered from MI.
Journal ArticleDOI
The inverse relation between fish consumption and 20-year mortality from coronary heart disease.
TL;DR: It is concluded that the consumption of as little as one or two fish dishes per week may be of preventive value in relation to coronary heart disease.
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