Journal ArticleDOI
Asymmetric synthesis of oxazolines bearing α-stereocenters through radical addition–enantioselective protonation enabled by cooperative catalysis
TLDR
In this paper, an efficient radical conjugate addition/enanti-lective protonation process was developed for N-aryl glycines and alkenyl oxazolines enabled by the cooperative photoredox catalysis and chiral phosphoric acid catalysis.Abstract:
An efficient radical conjugate addition/enantioselective protonation process was developed for N-aryl glycines and alkenyl oxazolines enabled by the cooperative photoredox catalysis and chiral phosphoric acid catalysis, which generated a series of chiral oxazolines bearing an α-stereocenter with high enantioselectivities. The facile transformations of the chiral oxazoline products into enantioenriched lactams and γ-amino esters bearing α-stereocenters demonstrate the value of this method.read more
Citations
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Journal ArticleDOI
Oxygen-Doped Carbon Nitride for Enhanced Photocatalytic Activity in Visible-Light-Induced Decarboxylative Annulation Reactions
Anzai Shi,Kai Sun,Yanxuan Wu,Panjie Xiang,Igor B. Krylov,Alexander O. Terent'ev,Xiaolan Chen,Bin Yu +7 more
TL;DR: An oxygen atom-doped modification strategy was developed to improve the photocatalytic activity of graphite-like carbon nitride (g-C3N4), which was successfully employed as a reusable photocatalyst in the cascade annulation reaction of N-sulfonyl ketimines with N-aryl glycines as discussed by the authors .
Journal ArticleDOI
Highly Enantioselective δ–Protonation and Formal [3+3] Annulation Promoted by N-Heterocyclic Carbene
TL;DR: An N-heterocyclic carbene (NHC) catalyzed highly enantioselective δ-protonation of α,β-γ,δ-diunsaturated aldehydes is described in this paper.
Journal ArticleDOI
Relay Organophotoredox/N-Heterocyclic Carbene Catalysis-Enabled Asymmetric Synthesis of Dibenzoxazepine-Fused Pyrrolidinones.
TL;DR: In this paper , an unprecedented highly stereoselective synthesis of pyrrolo[1,2-d][1,4]oxazepin-3(2H)-ones has been accomplished via photoredox/N-heterocyclic carbene (NHC) relay catalysis.
References
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Journal ArticleDOI
Organic Photoredox Catalysis
TL;DR: An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.
Journal ArticleDOI
Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates
Journal ArticleDOI
Enantioselective Mannich‐Type Reaction Catalyzed by a Chiral Brønsted Acid
Journal ArticleDOI
Chiral Brønsted acid-catalyzed direct Mannich reactions via electrophilic activation.
Daisuke Uraguchi,Masahiro Terada +1 more
TL;DR: It was found that the phosphoric acid derivatives of general structure 1 serve as highly effective catalysts for the direct addition of acetyl acetone to N-Boc-protected arylimines and functions as an excellent catalyst.