Attitudes towards and participation in randomised clinical trials in oncology: A review of the literature
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TLDR
There is a paucity of research examining the association between knowledge about clinical trials, anxiety associated with a new cancer diagnosis and willingness to participate in randomised clinical trials.About:
This article is published in Annals of Oncology.The article was published on 2000-08-01 and is currently open access. It has received 265 citations till now. The article focuses on the topics: Clinical study design & Clinical trial.read more
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Public Attitudes Toward Participation in Cancer Clinical Trials
TL;DR: The results indicate that the primary problem with accrual is not the attitudes of patients, but rather that the loss of potential participants is the result of the unavailability of an appropriate clinical trial and the disqualification of large numbers of patients.
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Improving the Evidence Base for Treating Older Adults With Cancer: American Society of Clinical Oncology Statement
Arti Hurria,Laura A. Levit,William Dale,Supriya G. Mohile,Hyman B. Muss,Louis Fehrenbacher,Allison Magnuson,Stuart M. Lichtman,Suanna S. Bruinooge,Enrique Soto-Perez-de-Celis,William P. Tew,Michael A. Postow,Harvey J. Cohen +12 more
TL;DR: The American Society of Clinical Oncology convened a subcommittee to develop recommendations on improving the evidence base for treating older adults with cancer in response to a critical need identified by the Institute of Medicine.
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Reasons for participating in randomised controlled trials: conditional altruism and considerations for self.
TL;DR: Recognition of conditional altruism has implications for planning trial recruitment communications to promote informed and voluntary trial participation and to recognise that participation will benefit them personally.
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Randomized Clinical Trials in Oncology: Understanding and Attitudes Predict Willingness to Participate
TL;DR: It is suggested that women who have a better understanding of issues about clinical trials have more favorable attitudes toward randomized trials and are more willing to consider participation in a clinical trial.
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Research into complementary and alternative medicine: problems and potential.
TL;DR: The growing use of unsubstantiated complementary and alternative medicine therapies by people in the United States along with its increasing coverage by third party payers encouraged Congress to create the National Center for Complementary and Alternative Medicine (NCCAM) at the National Institutes of Health to explore complementary andAlternative Medicine practices in the context of rigorous science.
References
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Evidence based medicine: what it is and what it isn't.
TL;DR: Evidence Based Medicine (IBM) as discussed by the authors is the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients, which is a hot topic for clinicians, public health practitioners, purchasers, planners and the public.
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Evidence-Based Medicine: A New Approach to Teaching the Practice of Medicine
Gordon H. Guyatt,John A. Cairns,David N. Churchill,Deborah J. Cook,Brian Haynes,Jack Hirsh,Jan Irvine,Mark Levine,Mitchell Levine,Jim Nishikawa,David L. Sackett,Patrick Brill-Edwards,Hertzel C. Gerstein,James L. Gibson,Roman Jaeschke,Anthony Kerigan,Alan J. Neville,Akbar Panju,Allan S. Detsky,Murray Enkin,Pamela Frid,Martha S. Gerrity,Andreas Laupacis,Valerie A. Lawrence,Joël Ménard,Virginia Moyer,Cynthia D. Mulrow,Paul Links,Andrew D Oxman,Jack Sinclair,Peter Tugwell +30 more
TL;DR: An important goal of the medical residency program is to educate physicians in the practice of evidence-based medicine, and strategies include a weekly, formal academic half-day for residents devoted to learning the necessary skills.
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Equipoise and the ethics of clinical research.
TL;DR: An alternative concept of equipoise is suggested, which would be based on present or imminent controversy in the clinical community over the preferred treatment, which is satisfied if there is genuine uncertainty within the expert medical community--not necessarily on the part of the individual investigator--about the preferredreatment.
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Information and participation preferences among cancer patients
TL;DR: Most patients in each age group displayed high levels of hope, preferences for open communication about their illness, and a desire for maximum amounts of information.
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Information Needs and Decisional Preferences in Women With Breast Cancer
Lesley F. Degner,Linda J. Kristjanson,David M. Bowman,Jeff A. Sloan,Keumhee C. Carriere,John O’Neil,Barbara Bilodeau,Peter H. Watson,Bryan Mueller +8 more
TL;DR: Priorities for information identified in this study provide an empirical basis to guide communication with women seeking care for breast cancer and suggest systematic approaches to assess and respond to women's desired level of participation in treatment decision making need to be evaluated.