Autosomal, mtDNA, and Y-Chromosome Diversity in Amerinds: Pre- and Post-Columbian Patterns of Gene Flow in South America
Natalia Mesa,María Cecilia Mondragón,Iván Soto,María Victoria Parra,Constanza Duque,Daniel Ortiz-Barrientos,Luis F. García,Iván D. Vélez,María Luisa Bravo,Juan G. Múnera,Gabriel Bedoya,Maria Cátira Bortolini,Maria Cátira Bortolini,Andres Ruiz-Linares,Andres Ruiz-Linares +14 more
TLDR
Admixture analysis of the Colombian populations suggests an asymmetric pattern of mating involving mostly immigrant men and native women, and the concordance of these estimates does not support an important difference in migration rates between the sexes throughout the history of South Amerinds.Abstract:
To evaluate sex-specific differences in gene flow between Native American populations from South America and between those populations and recent immigrants to the New World, we examined the genetic diversity at uni- and biparental genetic markers of five Native American populations from Colombia and in published surveys from native South Americans. The Colombian populations were typed for five polymorphisms in mtDNA, five restriction sites in the β-globin gene cluster, the DQA1 gene, and nine autosomal microsatellites. Elsewhere, we published results for seven Y-chromosome microsatellites in the same populations. Autosomal polymorphisms showed a mean GST of 6.8%, in agreement with extensive classical marker studies of South American populations. MtDNA and Y-chromosome markers resulted in GST values of 0.18 and 0.165, respectively. When only Y chromosomes of confirmed Amerind origin were used in the calculations (as defined by the presence of allele T at locus DYS199), GST increased to 0.22. GST values calculated from published data for other South American natives were 0.3 and 0.29 for mtDNA and Amerind Y chromosomes, respectively. The concordance of these estimates does not support an important difference in migration rates between the sexes throughout the history of South Amerinds. Admixture analysis of the Colombian populations suggests an asymmetric pattern of mating involving mostly immigrant men and native women.read more
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Advances in our understanding of mammalian sex-biased dispersal.
TL;DR: A review of mammalian data indicates that the relationship between direction of sex‐bias and mating system is not a simple one, and there is still need for a theoretical framework that can account for the complex interactions between inbreeding avoidance, kin competition and cooperation to explain the impressive diversity of patterns.
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Inferring sex-biased dispersal from population genetic tools: a review
Franck Prugnolle,T. De Meeûs +1 more
TL;DR: Different methods for inferring sex-specific dispersal using population genetic tools are described and the problems they can raise are discussed and the relative power of these methods is not well known and requires further investigation.
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Forensic DNA Evidence Interpretation
TL;DR: The Frequentist Approaches Bayesian Approaches Statistical Evaluation of Mixtures Low Copy Number and Interpretation Issues Associated with DNA Databases are discussed.
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Strong Amerind/white sex bias and a possible Sephardic contribution among the founders of a population in northwest Colombia.
Luis G. Carvajal-Carmona,Iván Soto,Nicolás Pineda,Daniel Ortiz-Barrientos,Constanza Duque,Jorge Ospina-Duque,Mark I. McCarthy,Patricia Montoya,Victor Alvarez,Gabriel Bedoya,Andres Ruiz-Linares,Andres Ruiz-Linares +11 more
TL;DR: A highly asymmetric pattern of mating in early Antioquia, involving mostly immigrant men and local native women is indicated, with the frequency of the four Amerind founder lineages being closest to Native Americans currently living in the area.
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Hierarchical Patterns of Global Human Y-Chromosome Diversity
Michael F. Hammer,Tatiana M. Karafet,Alan J. Redd,Hamdi Jarjanazi,S. Santachiara-Benerecetti,Himla Soodyall,Stephen L. Zegura +6 more
TL;DR: A nested cladistic analysis (NCA) demonstrated that both population structure processes (recurrent gene flow restricted by isolation by distance and long-distance dispersals) and population history events were instrumental in explaining this tripartite division of global NRY diversity.
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