Journal ArticleDOI
Bacillus thuringiensis CryIA(a) insecticidal toxin: crystal structure and channel formation.
Pawel Grochulski,Luke Masson,Svetlana Borisova,Marianne Pusztai-Carey,Jean-Louis Schwartz,Roland Brousseau,Miroslaw Cygler +6 more
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TLDR
Comparison with the structure of CryIIIA, a coleopteran-specific toxin, shows that although the fold of these two proteins is similar, there are significant structural differences within domain II, which supports the conclusions from genetic studies that domain II is involved in recognition and binding to cell surface receptors.About:
This article is published in Journal of Molecular Biology.The article was published on 1995-12-01. It has received 585 citations till now. The article focuses on the topics: Protein structure & Multiple isomorphous replacement.read more
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Journal ArticleDOI
Bacillus thuringiensis and Its Pesticidal Crystal Proteins
E. Schnepf,Neil Crickmore,J. Van Rie,Didier Lereclus,J. Baum,Jerald S. Feitelson,Daniel R. Zeigler,Donald H. Dean +7 more
TL;DR: Researchers are reporting promising results in engineering more-useful toxins and formulations, in creating transgenic plants that express pesticidal activity, and in constructing integrated management strategies to insure that these products are utilized with maximum efficiency and benefit.
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Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control.
TL;DR: Recent evidence suggests that Cyt synergize or overcome resistance to mosquitocidal-Cry proteins by functioning as a Cry-membrane bound receptor, and compares them to the mode of action of other bacterial PFT.
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Developments in the use of Bacillus species for industrial production
TL;DR: Developments from the understanding of the complex protein translocation machinery of Gram-positive bacteria should allow the resolution of current secretion challenges and make Bacillus species preeminent hosts for heterologous protein production.
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Insect pathogens as biological control agents: Back to the future.
Lawrence A. Lacey,David Grzywacz,David I. Shapiro-Ilan,Roger Frutos,M. Brownbridge,Mark S. Goettel +5 more
TL;DR: Current information on development, use and future directions of insect-specific viruses, bacteria, fungi and nematodes as components of integrated pest management strategies for control of arthropod pests of crops, forests, urban habitats, and insects of medical and veterinary importance is presented.
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Bacillus thuringiensis: A story of a successful bioinsecticide
TL;DR: Recently, similar Cry-binding proteins have been identified in the three insect orders, as cadherin, aminopeptidase-N and alkaline phosphatase suggesting a conserved mode of action, suggesting a significant reduction in chemical insecticide use.