Book ChapterDOI
Basic Substance Characteristics and Neuropathological Findings in Drug Abusers
Andreas Büttner
- pp 23-87
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TLDR
In this article, the major psychoactive component, ∆9tetrahydrocannabinol (∆9-THC), interacts with specific CB receptors in the brain.Abstract:
Cannabis is the most frequently abused recreational drug worldwide. Its major psychoactive component, ∆9-tetrahydrocannabinol (∆9-THC), interacts with specific cannabinoid (CB) receptors in the brain. Until today distinct neuropathological alterations have not been described.read more
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Journal ArticleDOI
Acute myelopathy following intravenous heroin: a case report.
TL;DR: A 43-year-old woman developed acute paraplegia and a Korsakoff syndrome following intravenous administration of heroin, probably due to spinal cord infarction resulting from systemic hypoxemia and hypotension.
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Brain abscess complicating drug abuse.
Takahito Hayashi,Takahito Hayashi,Claas T. Buschmann,Dejana Matejic,Benno Riesselmann,Michael Tsokos +5 more
TL;DR: A 29-year-old man was admitted to hospital to undergo a methadone maintenance treatment program as a withdrawal method for illicit drugs and showed frequent paroxysmal hypoxia, finally lapsing into a coma; the man died shortly thereafter.
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A deadly trend in fentanyl fatalities (England, 1998–2017)
TL;DR: The increasing availability of both pharmaceutical fentanyls and NPFDs represents a serious risk to public health in England and is contributing to the exponential increase in fentanyl-associated deaths that is being observed at the global scale.
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Another fatal case related to the recreational abuse of U-47700
Nadine Strehmel,Denise Dümpelmann,Elke Vejmelka,Veronika Strehmel,Sonja Roscher,Stefan Scholtis,Michael Tsokos +6 more
TL;DR: A non-targeted liquid chromatography/mass spectrometry (LC/MS)-based screening approach of urine and cerebrospinal fluid samples after intravenous injection of trans-3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide (U-47700) shows that the powder had a relatively high purity and was adulterated to a low degree.
Journal ArticleDOI
The symmetry of self mutilation and the chess board pattern.
TL;DR: Self inflicted incised wounds tend to have characteristic pathological features, occurring in clusters of superficial incised lesions of similar depth, and one of the most telling features is symmetry, with similar lesions sometimes being cut into opposite limbs.