Book ChapterDOI
Basic Substance Characteristics and Neuropathological Findings in Drug Abusers
Andreas Büttner
- pp 23-87
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TLDR
In this article, the major psychoactive component, ∆9tetrahydrocannabinol (∆9-THC), interacts with specific CB receptors in the brain.Abstract:
Cannabis is the most frequently abused recreational drug worldwide. Its major psychoactive component, ∆9-tetrahydrocannabinol (∆9-THC), interacts with specific cannabinoid (CB) receptors in the brain. Until today distinct neuropathological alterations have not been described.read more
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Journal ArticleDOI
Oxidative stress enzymes are changed in opioid abusers and multidrug abusers
Mitra-Sadat Sadat-Shirazi,Mohammad-Reza Zarrindast,Mohammad-Reza Zarrindast,Ghorbangol Ashabi +3 more
TL;DR: The results indicated that the level of MDA was increased in the mPFC, lPFC and OFC of pure-opioid and multi-drug abusers compared with the control group, which might be due to the increase of dopamine or the direct effect of opioids and other drugs of abuse on oxidative agents.
Journal ArticleDOI
Intracranial haemorrhage caused by amphetamine abuse.
M P A Lessing,N M Hyman +1 more
TL;DR: Investigation revealed positive serology for cysticercosis by an ELISA method, which revealed a large cyst within the cervical cord which was thought initially to be a syrinx.
Journal ArticleDOI
Drug-induced bilateral ischemic infarction in an amphetamine addict
TL;DR: A 33-year old Caucasian male amphetamine addict died at an intensive care unit due to bilateral cerebral infarction complicated by multi-organ failure, two days prior to admission he had taken several illegally bought pills, allegedly amphetamine and methamphetamine.
Journal ArticleDOI
Characteristics of methadone-related fatalities in Norway.
Jean-Paul Bernard,Hassan Z. Khiabani,Thor Hilberg,Ritva Karinen,Lars Slørdal,Helge Waal,Jørg Mørland +6 more
TL;DR: Results suggest that some patients may be at risk of dying when combining therapeutic concentrations of methadone with other psychoactive substances, both alone and in combination with other drugs.
Journal ArticleDOI
In-hospital outcomes of aneurysmal subarachnoid hemorrhage associated with cocaine use in the USA
TL;DR: In-hospital outcomes in a large population based study of aneurysmal subarachnoid hemorrhage with cocaine use were explored and cocaine use was found to be independently associated with poor outcomes, particularly higher mortality and lower home discharge rates.