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Bionic ankle–foot prosthesis normalizes walking gait for persons with leg amputation

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TLDR
This work compared metabolic energy costs, preferred velocities and biomechanical patterns of seven people with a unilateral transtibial amputation using the bionic prosthesis and using their own passive-elastic prosthesis to those of seven non-amputees during level-ground walking.
Abstract
Over time, leg prostheses have improved in design, but have been incapable of actively adapting to different walking velocities in a manner comparable to a biological limb. People with a leg amputation using such commercially available passive-elastic prostheses require significantly more metabolic energy to walk at the same velocities, prefer to walk slower and have abnormal biomechanics compared with non-amputees. A bionic prosthesis has been developed that emulates the function of a biological ankle during level-ground walking, specifically providing the net positive work required for a range of walking velocities. We compared metabolic energy costs, preferred velocities and biomechanical patterns of seven people with a unilateral transtibial amputation using the bionic prosthesis and using their own passive-elastic prosthesis to those of seven non-amputees during level-ground walking. Compared with using a passive-elastic prosthesis, using the bionic prosthesis decreased metabolic cost by 8 per cent, increased trailing prosthetic leg mechanical work by 57 per cent and decreased the leading biological leg mechanical work by 10 per cent, on average, across walking velocities of 0.75–1.75 m s−1 and increased preferred walking velocity by 23 per cent. Using the bionic prosthesis resulted in metabolic energy costs, preferred walking velocities and biomechanical patterns that were not significantly different from people without an amputation.

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Journal ArticleDOI

Principles of Neural Science

Michael P. Alexander
- 06 Jun 1986 - 
TL;DR: The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or her own research.
Journal ArticleDOI

Human-in-the-loop optimization of exoskeleton assistance during walking.

TL;DR: A method for identifying the exoskeleton assistance that minimizes human energy cost during walking is developed, which was effective with exoskeletons worn on one or both ankles, during a variety of walking conditions, during running, and when optimizing muscle activity.
Journal ArticleDOI

Biorobotics: Using robots to emulate and investigate agile locomotion

TL;DR: The goals of biorobotics are to take inspiration from biological principles to design robots that match the agility of animals, and to use robots as scientific tools to investigate animal adaptive behavior.
Journal ArticleDOI

Active lower limb prosthetics: a systematic review of design issues and solutions.

TL;DR: This paper presents a review on design issues and solutions found in active lower limb prostheses based on a systematic literature search with a methodical search strategy.
References
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Principles of Neural Science

TL;DR: The principles of neural science as mentioned in this paper have been used in neural networks for the purpose of neural network engineering and neural networks have been applied in the field of neural networks, such as:
Journal ArticleDOI

Principles of Neural Science

Michael P. Alexander
- 06 Jun 1986 - 
TL;DR: The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or her own research.
Journal ArticleDOI

The energy expenditure of normal and pathologic gait.

Robert L. Waters, +1 more
- 01 Jul 1999 - 
TL;DR: The purpose of this review is to outline the basic principles of exercise physiology relevant to human locomotion; detail the energy expenditure of normal walking; and summarize the results of energy expenditure studies performed in patients with specific neurologic and orthopedic disabilities.
Journal ArticleDOI

Mechanical work for step-to-step transitions is a major determinant of the metabolic cost of human walking

TL;DR: Mechanical work for step-to-step transitions, rather than pendular motion itself, appears to be a major determinant of the metabolic cost of walking.
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