Journal ArticleDOI
Biosensors employing ionic self-assembled multilayers adsorbed on long-period fiber gratings
Zhiyong Wang,James R. Heflin,Kevin E. Van Cott,Rogers H. Stolen,Siddharth Ramachandran,Samir Ghalmi +5 more
TLDR
In this paper, an ionic self-assembled multilayers (ISAM) adsorbed on long period gratings (LPGs) function effectively as biosensors using biotin-streptavidin as a demonstration bioconjugate pair.Abstract:
We demonstrate that ionic self-assembled multilayers (ISAMs) adsorbed on long period gratings (LPGs) function effectively as biosensors using biotin–streptavidin as a demonstration bioconjugate pair. Biotin, streptavidin, and anti-streptavidin were deposited onto the ISAM-coated LPG sequentially, each inducing a measurable resonant wavelength shift of the LPG. Control experiments verified the specificity of the biosensor system. Furthermore, we demonstrate that ISAM coated turnaround point LPGs could serve as highly sensitive biosensors that exhibit a change in transmitted intensity rather than resonant wavelength. Experimental measurements confirm that ISAM-coated LPGs provide an attractive platform for building efficient and high-performance optical sensors.read more
Citations
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Journal ArticleDOI
Biosensing with optical fiber gratings
TL;DR: In this article, the authors review the recent development in OFG-based biosensing and identify some of the key challenges for practical applications, while there are still open questions pertaining to an effective and reliable detection of small molecules, possibly up to single molecule, sensing in vivo and multi-target detection using OFGbased technology platforms.
Journal ArticleDOI
Giant sensitivity of long period gratings in transition mode near the dispersion turning point: an integrated design approach
TL;DR: An original design approach based on the modal dispersion curves for the development of long period gratings in transition mode near the dispersion turning point exhibiting ultrahigh refractive index sensitivity places thin film coated LPGs as an alternative to other fiber-based technologies for high-performance chemical and biological sensing applications.
Journal ArticleDOI
Optical fibre gratings as tools for chemical and biochemical sensing.
Francesco Baldini,Massimo Brenci,Francesco Chiavaioli,Francesco Chiavaioli,Ambra Giannetti,Cosimo Trono +5 more
TL;DR: The fundamentals of the different types of optical fibre gratings are described and the performances of the chemical and biochemical sensors based on this approach are reviewed, with a look at new perspectives for their utilization in the field.
Journal ArticleDOI
Detection of bacteria using bacteriophages as recognition elements immobilized on long-period fiber gratings.
TL;DR: This paper presents for the first time a study of long-period gratings applied for label-free detection of specific bacteria using physically adsorbed bacteriophages, and shows that the device allows for real-time monitoring of phenomena taking place on the sensor's surface, including phage-bacteria interactions.
Journal ArticleDOI
Sol–Gel-Based Titania–Silica Thin Film Overlay for Long Period Fiber Grating-Based Biosensors
Francesco Chiavaioli,Palas Biswas,Cosimo Trono,Sunirmal Jana,Somnath Bandyopadhyay,Nandini Basumallick,Ambra Giannetti,Sara Tombelli,Susanta Bera,Aparajita Mallick,Francesco Baldini +10 more
TL;DR: An evanescent wave optical fiber biosensor based on titania-silica-coated long period grating (LPG) is presented and is proposed as an effective and feasible label-free biosensor.
References
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Journal ArticleDOI
Fuzzy Nanoassemblies: Toward Layered Polymeric Multicomposites
TL;DR: In this article, a general approach for multilayers by consecutive adsorption of polyanions and polycations has been proposed and has been extended to other materials such as proteins or colloids.
Long-period fiber grating as band-rejection filters
TL;DR: In this paper, a new class of long-period fiber gratings that can be used as in-fiber, low-loss, band-rejection filters is presented.
Journal ArticleDOI
Long-period fiber gratings as band-rejection filters
Ashish Madhukar Vengsarkar,Paul Joseph Lemaire,J. B. Judkins,Vikram Bhatia,Turan Erdogan,John E. Sipe +5 more
TL;DR: In this paper, a new class of long-period fiber gratings that can be used as in-fiber, low-loss, band-rejection filters is presented.
Journal ArticleDOI
Analysis of the response of long period fiber gratings to external index of refraction
TL;DR: In this article, the authors demonstrate that the change in wavelength of a long period fiber grating attenuation band with changes in external index of refraction can be enhanced by proper selection of the grating period.
Journal ArticleDOI
Sensitivity characteristics of long-period fiber gratings
Xuewen Shu,Lin Zhang,Ian Bennion +2 more
TL;DR: In this paper, the sensitivity of long-period fiber gratings (LPFGs) is investigated as a function of temperature, strain, and surrounding refractive index, with particular attention to the higher order cladding modes and the possibilities for ultrasensitive sensors.