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Journal ArticleDOI

Bivalirudin versus heparin as an anticoagulant during extracorporeal membrane oxygenation: a case-control study.

TLDR
Bivalirudin-based antICOagulation may represent a new method of anticoagulation for reducing thromboembolic and bleeding complications, which still jeopardize the application of extracorporeal membrane oxygenation.
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This article is published in Journal of Cardiothoracic and Vascular Anesthesia.The article was published on 2013-02-01. It has received 149 citations till now. The article focuses on the topics: Bivalirudin & Extracorporeal membrane oxygenation.

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Citations
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2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery.

TL;DR: Authors/Task Force Members: Christa Boer (EACTA Chairperson) and Michael I. Meesters (Netherlands), Milan Milojevic (N Netherlands), Umberto Benedetto (UK), Daniel Bolliger (Switzerland), Christian von Heymann (Germany), Anders Jeppsson (Sweden), Andreas Koster (Germany).
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Bleeding and Thrombotic Complications in the Use of Extracorporeal Membrane Oxygenation

TL;DR: Achieving the optimal anticoagulation balance to prevent bleeding and thrombosis in ECMO patients is extremely complex and experts in hemostasis should be a part of an institutional ECMO team and continuously available for immediate management.
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2015 SCAI/ACC/HFSA/STS Clinical Expert Consensus Statement on the Use of Percutaneous Mechanical Circulatory Support Devices in Cardiovascular Care

TL;DR: This data indicates that the use of an intra-aortic balloon pump for women with high aortic aneurysm prolapse preoperatively and then on the basis of prior history and once they provide informed consent for the pump to be switched to a women's only device is a viable option.
References
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Journal ArticleDOI

Treatment and Prevention of Heparin-Induced Thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)

TL;DR: In this paper, the recognition, treatment, and prevention of heparin-induced thrombocytopenia (HIT) is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
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Risk for heparin-induced thrombocytopenia with unfractionated and low- molecular-weight heparin thromboprophylaxis: a meta-analysis

TL;DR: The objective was to determine and compare the incidences of HIT in surgical and medical patients receiving thromboprophylaxis with either UFH or LMWH and to favor the use of LMWH.
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Review of ECMO (extra corporeal membrane oxygenation) support in critically ill adult patients.

TL;DR: The technical aspects of ECMO cannulation, maintenance and weaning are outlined, Complication rates and outcomes are reviewed, and the experience at The Epworth Hospital is summarized.
Journal ArticleDOI

Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction.

TL;DR: Abciximab and unfractionated heparin, as compared with bivalirudin, failed to reduce the rate of the primary end point and increased the risk of bleeding among patients with non-ST-segment elevation myocardial infarction who were undergoing PCI.
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Beyond Unfractionated Heparin and Warfarin Current and Future Advances

TL;DR: With advances in structure-based design, most new anticoagulants are small molecules designed specifically to block the activity of coagulation enzymes either by fitting into their catalytic pockets, like a key into a lock, or by interacting with and activating antICOagulant proteins such as antithrombin (AT; eg, fondaparinux).
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