Journal ArticleDOI
Brain-derived neurotrophic factor plasma variation during the different phases of the menstrual cycle in women with premenstrual syndrome
Alessandra Cubeddu,Fiorella Bucci,Andrea Giannini,Marinella Russo,Diana Daino,Natalia Russo,Sara Merlini,Nicola Pluchino,Valeria Valentino,Elena Casarosa,Stefano Luisi,Andrea R. Genazzani +11 more
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TLDR
In women with PMS, plasma BDNF followed a decreasing trend during the ovarian cycle, in opposition to the increasing trend observed in women without PMS.About:
This article is published in Psychoneuroendocrinology.The article was published on 2011-05-01. It has received 83 citations till now. The article focuses on the topics: Luteal phase & Menstrual cycle.read more
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Stress effects on BDNF expression: Effects of age, sex, and form of stress
TL;DR: Stress-induced alterations in growth factors, in particular brain-derived neurotrophic factor (BDNF), have been identified as a strong candidate modulating stress-associated pathology and changing expression of BDNF and its receptors over development and in response to circulating gonadal hormones extend the attractiveness of this candidate signaling pathway for understanding differences in susceptibility to stress.
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Premenstrual Dysphoric Disorder: Epidemiology and Treatment
Liisa Hantsoo,C. Neill Epperson +1 more
TL;DR: Recent literature on potential contributors to premenstrual dysphoric disorder’s pathophysiology, including neurosteroids and stress, are presented, and potential treatment targets are explored.
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Steroid hormones and BDNF.
TL;DR: This overview aims to summarize the current knowledge on the correlation between BDNF expression/function and both gonadal (progesterone, estrogens, and testosterone) and adrenal hormones and DHEA with relevance in clinical application.
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Brain Derived Neurotrophic Factor: epigenetic regulation in psychiatric disorders.
Cathy Mitchelmore,Lene Gede +1 more
TL;DR: The current knowledge of BDNF epigenetic regulation with respect to psychiatric disorders is summarized and how this information can be applied in therapy and future research is described.
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Variant Brain-Derived Neurotrophic Factor (Valine66Methionine) Polymorphism Contributes to Developmental and Estrous Stage-Specific Expression of Anxiety-Like Behavior in Female Mice
Kevin G. Bath,Jocelyn Chuang,Joanna L. Spencer-Segal,Dima Amso,Margaret Altemus,Bruce S. McEwen,Francis S. Lee +6 more
TL;DR: Findings have implications regarding the potential role of this SNP in contributing to developmental and reproductive hormone-dependent changes in affective disorders in humans.
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Journal ArticleDOI
Neurotrophins and synaptic plasticity.
TL;DR: The evidence implicating neurotrophins as molecular mediators of synaptic and morphological plasticity, and the rules and mechanisms by which they exert their effects remain intriguingly elusive are discussed.
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Long-Lasting Neurotrophin-Induced Enhancement of Synaptic Transmission in the Adult Hippocampus
Hyejin Kang,Erin M. Schuman +1 more
TL;DR: Long-term potentiation could still be elicited in slices previously potentiated by exposure to the neurotrophic factors, which implies that these two forms of plasticity may use at least partially independent cellular mechanisms.
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Transport of brain-derived neurotrophic factor across the blood-brain barrier
TL;DR: It is concluded that intact BDNF in the peripheral circulation crosses the blood-brain barrier by a high-capacity, saturable transport system.