scispace - formally typeset
Open AccessJournal ArticleDOI

Breast cancer treatment: A phased approach to implementation.

Reads0
Chats0
TLDR
This strategy proposes that, after a situational analysis, implementation phases begin with bolstering palliative care capacity, especially in settings where a late‐stage diagnosis is common, followed by strengthening the patient pathway.
Abstract
Optimal treatment outcomes for breast cancer are dependent on a timely diagnosis followed by an organized, multidisciplinary approach to care. However, in many low- and middle-income countries, effective care management pathways can be difficult to follow because of financial constraints, a lack of resources, an insufficiently trained workforce, and/or poor infrastructure. On the basis of prior work by the Breast Health Global Initiative, this article proposes a phased implementation strategy for developing sustainable approaches to enhancing patient care in limited-resource settings by creating roadmaps that are individualized and adapted to the baseline environment. This strategy proposes that, after a situational analysis, implementation phases begin with bolstering palliative care capacity, especially in settings where a late-stage diagnosis is common. This is followed by strengthening the patient pathway, with consideration given to a dynamic balance between centralization of services into centers of excellence to achieve better quality and decentralization of services to increase patient access. The use of resource checklists ensures that comprehensive therapy or palliative care can be delivered safely and effectively. Episodic or continuous monitoring with established process and quality metrics facilitates ongoing assessment, which should drive continual process improvements. A series of case studies provides a snapshot of country experiences with enhancing patient care, including the implementation of national cancer control plans in Kenya, palliative care in Romania, the introduction of a 1-stop clinic for diagnosis in Brazil, the surgical management of breast cancer in India, and the establishment of a women's cancer center in Ghana.

read more

Citations
More filters
Journal ArticleDOI

Aptamer grafted nanoparticle as targeted therapeutic tool for the treatment of breast cancer

TL;DR: In this article , a review of aptamer-based biosensor in breast cancer diagnosis has been presented, and the appropriate usage of the aptamer based biosensor has also been discussed, where the authors showcase the method and modified method of selection of aptamers, aptamer that were able to make its way towards clinical trial and their targetability and selectivity towards breast cancers.
Journal ArticleDOI

Nanoparticles Targeting Receptors on Breast Cancer for Efficient Delivery of Chemotherapeutics.

TL;DR: The authors in this paper presented an overview of the principle of targeted delivery approaches, exploiting drug-nanoparticle conjugates with multiple targeting moieties to target specific receptors of breast cancer cells and highlighting therapeutic evaluation in preclinical studies.
Journal ArticleDOI

NCCN resource-stratified and harmonized guidelines: A paradigm for optimizing global cancer care

TL;DR: The critical need for local expertise and involvement in successful development and uptake is emphasized, and the promise of this collaboration for advancement in oncology programs is illustrated.
Journal ArticleDOI

Enhanced Cytotoxic Activity of Docetaxel-Loaded Silk Fibroin Nanoparticles against Breast Cancer Cells.

TL;DR: In this article, the authors presented the feasibility of using silk fibroin nanoparticles (SF-NPs) as a nontoxic biocompatible delivery vehicle for enhanced therapeutic outcomes in breast cancer.
References
More filters
Journal ArticleDOI

Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.

TL;DR: Lumpectomy followed by breast irradiation continues to be appropriate therapy for women with breast cancer, provided that the margins of resected specimens are free of tumor and an acceptable cosmetic result can be obtained.
Journal ArticleDOI

Twenty-Year Follow-up of a Randomized Study Comparing Breast-Conserving Surgery with Radical Mastectomy for Early Breast Cancer

TL;DR: The long-term survival rate among women who undergo breast-conserving surgery is the same as that among women Who undergo radical mastectomy, and Breast-conserve surgery is therefore the treatment of choice for women with relatively small breast cancers.
Journal ArticleDOI

Prevalence of pain in patients with cancer: a systematic review of the past 40 years

TL;DR: Pooled prevalence of pain was >50% in all cancer types with the highest prevalence in head/neck cancer patients (70%; 95% CI 51% to 88%).
Journal ArticleDOI

Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials

TL;DR: After mastectomy and axillary dissection, radiotherapy reduced both recurrence and breast cancer mortality in the women with one to three positive lymph nodes in these trials even when systemic therapy was given.
Related Papers (5)
Trending Questions (2)
Why can the phased implementation approach cause data inconsistencies and coordination issues?

The phased implementation approach can cause data inconsistencies and coordination issues due to varying levels of resources, workforce training, and infrastructure in low- and middle-income countries.

Why can the phased implementation approach in geographical locations cause data inconsistencies and coordination issues?

Phased implementation in geographical locations can cause data inconsistencies and coordination issues due to financial constraints, lack of resources, workforce training, and poor infrastructure in low- and middle-income countries.