Cardiac remodeling—concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling
TLDR
Left ventricular end-diastolic and end-systolic volume and ejection fraction data provide support for the beneficial effects of therapeutic agents such as angiotensin-converting enzyme (ACE) inhibitors and beta-adrenergic blocking agents on the remodeling process.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2000-03-01 and is currently open access. It has received 2215 citations till now. The article focuses on the topics: Ventricular remodeling & Ejection fraction.read more
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A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure.
Jay N. Cohn,Gianni Tognoni +1 more
TL;DR: Valsartan significantly reduces the combined end point of mortality and morbidity and improves clinical signs and symptoms in patients with heart failure, when added to prescribed therapy, and raises concern about the potential safety of this specific combination.
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Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial
Kai C. Wollert,Gerd Peter Meyer,Joachim Lotz,Stefanie Ringes Lichtenberg,Peter Lippolt,Christiane Breidenbach,Stephanie Fichtner,Thomas Korte,Burkhard Hornig,Diethelm Messinger,Lubomir Arseniev,Bernd Hertenstein,Arnold Ganser,Helmut Drexler +13 more
TL;DR: Intracoronary transfer of autologous bone-marrow-cells promotes improvement of left-ventricular systolic function in patients after acute myocardial infarction.
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Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing.
Virend K. Somers,David P. White,Raouf S. Amin,William T. Abraham,Fernando Ferreira Costa,Antonio Culebras,Stephen R. Daniels,John S. Floras,Carl E. Hunt,Lyle J. Olson,Thomas G. Pickering,Richard O. Russell,Mary Woo,Terry Young +13 more
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Sleep Apnea and Cardiovascular Disease An American Heart Association/American College of Cardiology Foundation Scientific Statement From the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing In Collaboration With the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health)
Virend K. Somers,David P. White,Raouf S. Amin,William T. Abraham,Fernando Ferreira Costa,Antonio Culebras,Stephen R. Daniels,John S. Floras,Carl E. Hunt,Lyle J. Olson,Thomas G. Pickering,Richard O. Russell,Mary Woo,Terry Young +13 more
TL;DR: This first American Heart Association/American College of Cardiology Scientific Statement on Sleep Apnea and Cardiovascular Disease seeks to highlight concepts and evidence important to understanding the interactions between sleep apnea and cardiovascular disease, with particular attention to more recent advances in patient-oriented research.
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Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function
TL;DR: The purpose of this review is to examine and redefine the myocardial matrix as a critical and dynamic entity with respect to the remodeling process encountered with MI, hypertension, or cardiomyopathic disease, and to dispel the historical belief that the myCardial matrix is a passive structure.
References
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Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure.
TL;DR: The addition of enalapril to conventional therapy significantly reduced mortality and hospitalizations for heart failure in patients with chronic congestive heart failure and reduced ejection fractions.
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Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. results of the survival and ventricular enlargement trial
Marc A. Pfeffer,Eugene Braunwald,Lemuel A. Moyé,Lofty L. Basta,Edward J. Brown,Thomas E. Cuddy,Barry R. Davis,Edward M. Geltman,Steven Goldman,Greg C. Flaker,Marc Klein,Gervasio A. Lamas,Milton Packer,Jacques R. Rouleau,Jean L. Rouleau,John D. Rutherford,John H. Wertheimer,C. Morton Hawkins +17 more
TL;DR: In patients with asymptomatic left ventricular dysfunction after myocardial infarction, long-term administration of captopril was associated with an improvement in survival and reduced morbidity and mortality due to major cardiovascular events.
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Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
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The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial
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