Journal ArticleDOI
Cardio-Onco-Hematología en la práctica clínica. Documento de consenso y recomendaciones
Teresa López-Fernández,Ana Martín García,Ana Santaballa Beltrán,Ángel Montero Luis,Ramón García Sanz,Pilar Mazón Ramos,Sonia Velasco del Castillo,Esteban López de Sá y Areses,Manuel Barreiro-Pérez,Rocío Hinojar Baydes,Leopoldo Pérez de Isla,Silvia Cayetana Valbuena López,Regina Dalmau González-Gallarza,Francisco Calvo-Iglesias,Juan José González Ferrer,Antonio Castro Fernández,Eva González-Caballero,Cristina Mitroi,Meritxell Arenas,Juan Antonio Virizuela Echaburu,Pascual Marco Vera,Andrés Íñiguez Romo,José Luis Zamorano,Juan Carlos Plana Gomez,José Luis López Sendón Henchel +24 more
TLDR
El objetivo ofrece actualizar los conocimientos aplicables a la practica clinica diaria de the cardio-onco-hematologia and promover el desarrollo of equipos multidisciplinarios locales that mejoren the salud cardiovascular of los pacientes con cancer.Abstract:
Resumen Los avances en la deteccion precoz y el tratamiento del cancer han reducido de manera significativa la mortalidad de los pacientes. Sin embargo, mejorar el pronostico no es solo curar el tumor, sino prevenir, diagnosticar y tratar eficazmente las complicaciones derivadas de las terapias onco-hematologicas. La toxicidad cardiovascular es un problema ampliamente reconocido con multiples esquemas terapeuticos; sin embargo, la evidencia cientifica en el manejo de las complicaciones cardiovasculares de pacientes onco-hematologicos es escasa, pues sistematicamente se ha excluido de los ensayos clinicos a estos enfermos y las recomendaciones actuales estan basadas en consensos de expertos. Es imprescindible crear equipos multidisciplinarios locales para optimizar los resultados en salud de los supervivientes al cancer. Una preocupacion excesiva por la aparicion de toxicidad cardiovascular puede impedir terapias potencialmente curativas, mientras que la subestimacion de este riesgo compromete el pronostico vital a largo plazo. El objetivo de este documento, elaborado en colaboracion con la Sociedad Espanola de Cardiologia, la Sociedad Espanola de Oncologia Medica, la Sociedad Espanola de Oncologia Radioterapica y la Sociedad Espanola de Hematologia, es actualizar los conocimientos aplicables a la practica clinica diaria de la cardio-onco-hematologia y promover el desarrollo de equipos multidisciplinarios locales que mejoren la salud cardiovascular de los pacientes con cancer.read more
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2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).
Alexander R. Lyon,Teresa López-Fernández,Liam Couch,Riccardo Asteggiano,Marianne C Aznar,Jutta Bergler-Klein,Giuseppe Boriani,Daniela Cardinale,Raul Cordoba,Bernard Cosyns,D Cutter,Evandro de Azambuja,W. De Boer,Susan Dent,Dimitrios Farmakis,Sofie Gevaert,D. Gorog,A. Herrmann,Daniel J. Lenihan,Javid Moslehi,Brenda Moura,Sonja S Salinger,R. Stephens,Thomas M. Suter,Sebastian Szmit,Juan Tamargo,Paaladinesh Thavendiranathan,Carlo G. Tocchetti,P. Van Der Meer,Helena J H van der Pal +29 more
Journal ArticleDOI
2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).
Alexander R. Lyon,Teresa López-Fernández,Liam Couch,Riccardo Asteggiano,Marianne C. Aznar,Jutta Bergler-Klein,Giuseppe Boriani,Daniela Cardinale,Raul Cordoba,Bernard Cosyns,D Cutter,Evandro de Azambuja,W. De Boer,Susan Dent,Dimitrios Farmakis,Sofie Gevaert,Diana A. Gorog,A. Herrmann,Daniel J. Lenihan,Javid Moslehi,Brenda Moura,Sonja S Salinger,R. Stephens,Thomas M. Suter,Sebastian Szmit,Juan Tamargo,Paaladinesh Thavendiranathan,Carlo G. Tocchetti,P. Van Der Meer,Helena J H van der Pal +29 more
Journal ArticleDOI
Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies. The OVERCOME trial (preventiOn of left Ventricular dysfunction with Enalapril and caRvedilol in patients submitted to intensive ChemOtherapy for the treatment of Malignant hEmopathies)
TL;DR: The present trial showed that a combination of enalapril and carvedilol might prevent cardiotoxicity in patients undergoing chemotherapy for hematological malignancies.
Journal ArticleDOI
Cardio-Oncology Services: rationale, organization, and implementation A report from the ESC Cardio-Oncology council
Patrizio Lancellotti,Thomas M. Suter,Teresa López-Fernández,Maurizio Galderisi,Alexander R. Lyon,Peter van der Meer,Alain Cohen Solal,José Luis Zamorano,Guy Jerusalem,Marie Moonen,Victor Aboyans,Jeroen J. Bax,Riccardo Asteggiano +12 more
TL;DR: This document from the ESC Cardio-Oncology council proposes the grounds for creating C-O Services in Europe based on expert opinion, and presents their rationale, organization, and implementation.
Journal ArticleDOI
Classification, prevalence, and outcomes of anticancer therapy-induced cardiotoxicity: the CARDIOTOX registry.
Jose Lopez-Sendon,Carlos Álvarez-Ortega,Pilar Zamora Auñón,Antonio Buño Soto,Alexander R. Lyon,Dimitrios Farmakis,Dimitrios Farmakis,Daniela Cardinale,Miguel Canales Albendea,Jaime Feliu Batlle,Isabel Rodríguez Rodríguez,Olaia Rodríguez Fraga,Ainara Albaladejo,Guiomar Mediavilla,José Ramón González-Juanatey,Amparo Martínez Monzonis,Pilar Gómez Prieto,José González-Costello,José María Serrano Antolín,Rosalía Cadenas Chamorro,Teresa López Fernández +20 more
TL;DR: The majority of patients present objective data of myocardial injury/dysfunction during or after cancer therapy, but severe CTox, with a strong prognostic relationship, was comparatively rare and should be reflected in protocols for clinical and research practices.
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