Journal ArticleDOI
Cavum septum pellucidum and its increased prevalence in schizophrenia: a neuroembryological classification.
Reads0
Chats0
TLDR
The neurodevelopmental theory of the septum pellucidum and its possible association with schizophrenia was focused on and the prevalence of a cavum was significantly higher in the patients with schizophrenia.Abstract:
Thirty-two female (mean age=52.9 years [SD=9.2]) patients with a diagnosis of residual schizophrenia and 19 female (mean age=51.1 years [SD=12.7]) control subjects were studied through cerebral Magnetic Resonance Imaging. Along the entire surface of the septum pellucidum, 1-mm coronal slices were performed in all subjects. The authors classified the cavum septum pellucidum into three types based on embryological development. The prevalence of a cavum was significantly higher in the patients with schizophrenia (Chi square 6.112. p < 0.05). No other significant associations with previously described morphological brain changes were found. Although this result was found in previous reports (DeGreef et al., 1992; DeLisi et al., 1993), our discussion focused on the neurodevelopmental theory of the septum pellucidum and its possible association with schizophrenia.read more
Citations
More filters
Journal ArticleDOI
Regulation of affect by the lateral septum: implications for neuropsychiatry
TL;DR: The lateral septum (LS) plays a critical role in regulating processes related to mood and motivation as mentioned in this paper, both through stimulating the activity of midbrain dopamine neurons and regulating the consequences of this activity on the ventral striatum.
Research report Regulation of affect by the lateral septum: implications for neuropsychiatry
TL;DR: The lateral septum (LS) plays a critical role in regulating processes related to mood and motivation as discussed by the authors, both through stimulating the activity of midbrain dopamine neurons and regulating the consequences of this activity on the ventral striatum.
Journal ArticleDOI
Ethanol-induced face-brain dysmorphology patterns are correlative and exposure-stage dependent.
Robert J. Lipinski,Peter Hammond,Shonagh K. O'Leary-Moore,Jacob J. Ament,Stephen J. Pecevich,Yi Jiang,Francois Budin,Scott E. Parnell,Michael Suttie,Elizabeth A. Godin,Joshua L. Everson,Deborah B. Dehart,Ipek Oguz,Hunter T. Holloway,Martin Styner,G. Allan Johnson,Kathleen K. Sulik +16 more
TL;DR: It is demonstrated that early prenatal ethanol exposure can cause more than one temporally-specific pattern of defects, and the need for an expansion of current diagnostic criteria is illustrated to better capture the full range of facial and brain dysmorphology in fetal alcohol spectrum disorders.
Journal ArticleDOI
Are cavum septum pellucidum abnormalities more common in schizophrenia spectrum disorders? A systematic review and meta-analysis.
Clarissa Trzesniak,Clarissa Trzesniak,Irismar Reis de Oliveira,Matthew J. Kempton,Amanda Galvão-de Almeida,Amanda Galvão-de Almeida,Marcos Hortes Nisihara Chagas,Maria Cecília Freitas Ferrari,Alaor Santos Filho,Antonio Waldo Zuardi,D. A. Prado,Geraldo F. Busatto,Phillip McGuire,Jaime Eduardo Cecílio Hallak,José Alexandre de Souza Crippa +14 more
TL;DR: Overall the results suggest that only a large CSP is associated with SSD while a small CSP may be considered a normal neuroanatomical variation.
Journal ArticleDOI
Cavum velum interpositum, cavum septum pellucidum, and cavum vergae: a review
R. Shane Tubbs,Sanjay Krishnamurthy,Ketan Verma,Mohammadali Mohajel Shoja,Marios Loukas,Martin M. Mortazavi,Aaron A. Cohen-Gadol +6 more
TL;DR: Anterior midline intracranial cysts may be found most often in three forms: cavum septum pellucidum, cavum vergae, and cavum velum interpositum.
References
More filters
Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Journal ArticleDOI
Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study.
Martha E. Shenton,Ron Kikinis,Ferenc A. Jolesz,Seth D. Pollak,Marjorie LeMay,Cynthia G. Wible,Hiroto Hokama,John D. Martin,Dave Metcalf,Michael J. Coleman,Robert W. McCarley +10 more
TL;DR: New MRI neuroimaging techniques are used to derive volume measurements and three-dimensional reconstructions of temporal-lobe structures in vivo in 15 right-handed men with chronic schizophrenia and 15 matched controls to discover the degree of thought disorder is related to the size of the reduction in volume of the left posterior superior temporal gyrus.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Basal Ganglia and Limbic System Pathology in Schizophrenia: A Morphometric Study of Brain Volume and Shrinkage
TL;DR: The volume reductions of the limbic temporal structures and of the pallidum internum of schizophrenics are interpreted as degenerative shrinkages of unknown etiology.