Journal ArticleDOI
Characteristics of response of renal vascular bed to contrast media. Evidence for vasoconstriction induced by renin-angiotensin system.
TLDR
The vasoconstrictor response to contrast media apparently is related to the hyper tonicity of these agents, activation of the renin-angiotensin system and the local conversion of angiotens in I to ang Elliotensin II within the kidney.Abstract:
Three contrast media (mcglumine diatrizoate, meglumine iothalamate and sodium diatrizoate) produced a characteristic biphasic renal hemodynamic response in dogs. An initial transient vasodilatation, which is the common response to contrast media of all vascular beds, was followed by a more prolonged period of vasoconstriction, which is unique to the kidney. Phenoxybenzamine blocked the renal vasoconstriction produced by norepinephrine and 5–hydroxytryptamine but did not influence the biphasic response to the contrast media. The vasoconstriction caused by a bolus of angiotensin or by the contrast media was completely abolished during angiotensin tachyphylaxis, however. Thus, neither norepinephrine nor 5–hydroxytryptamine was involved in mediating the vasoconstriction, whereas angiotensin was implicated. The vasoconstrictor response to contrast media apparently is related to the hyper tonicity of these agents, activation of the renin-angiotensin system and the local conversion of angiotensin I to angiotensin II within the kidney.read more
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Dissertation
Étude de la fonction vasculaire et du remodelage cardiaque avant l’établissement de l’obésité et de la dyslipidémie chez les rats femelles Sprague-Dawley recevant une diète riche en gras
TL;DR: L’administration orale chronique de l’antioxydant resveratrol (RES; 20 mg·kg-1·jr-1) a prevenu le developpement of ces alterations pathologiques, attestant d’une implication du stress oxydant.
Journal ArticleDOI
Angiotensin converting enzyme inhibitors and contrast-induced nephropathy.
TL;DR: The influence of angiotensin–converting enzyme inhibitor administration on the development of contrast-induced nephropathy was discussed in this letter.
Journal Article
Effects of two different treatments with continuous renal replacement therapy in patients with chronic renal dysfunction submitted to coronary invasive procedures.
Valentina Spini,Emanuele Cecchi,Marco Chiostri,Daniele Landi,Salvatore Mario Romano,Alessio Mattesini,Gian Franco Gensini,Cristina Giglioli +7 more
TL;DR: It is suggested that in CKD patients undergoing PCI,CRRT performed before and after is more effective in preventing a further deterioration of renal function and is associated with an improved long-term outcome when compared to CRRT performed only after.
Journal ArticleDOI
In vivo fluorescence microscopy of microcirculation in the renal cortex of mice. Part III. Effects of mannitol and iohexol infusions after pretreatment with cyclosporin A.
TL;DR: In vivo fluorescence microscopy was used for experimental studies of the renal cortical microcirculation in normal mice and in mice pretreated with the nephrotoxic drug cyclosporin A, and there was an initial rise in the number of capillaries with increased blood flow after infusions of both mannitol and iohexol.
Journal ArticleDOI
In Vivo Fluorescence Microscopy of Microcirculation in the Renal Cortex of Mice: Part II. Effects of Mannitol and Contrast Media Infusions
TL;DR: The renal cortical blood flow was inhomogeneous with respect to different capillaries and was to some extent simultaneously decreased in others, significantly more after infusion of metrizoate than before infusion of mannitol 0.3 mol/l.