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Journal ArticleDOI

Chronic childhood constipation is associated with impaired quality of life: a case-controlled study.

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TLDR
At initial evaluation, children with constipation have a lower quality of life than do children with inflammatory bowel disease or gastroesophageal reflux disease and self-reported lower scores may be a reflection of impaired physical ability.
Abstract
Objective: The objective of this study was to investigate the effect of chronic constipation on children's quality of life Methods: From October 2002 to November 2003, 224 children (140 male, 84 female, aged 106 ± 29 years) and 224 parents were evaluated by a health related quality of life tool during initial outpatient consultation Children with constipation (n = 80) were compared with controls with inflammatory bowel disease (n = 42), controls with gastroesophageal reflux disease (n = 56), and with healthy children (n = 46) Results: Children with constipation had lower quality of life scores than did those with inflammatory bowel disease (70 versus 84; P < 005), gastroesophageal reflux disease (70 versus 80; P < 005), and healthy children (70 versus 88; P < 005) Children with constipation reported lower physical scores than did inflammatory bowel disease patients (75 versus 85; P < 002), gastroesophageal reflux disease patients (75 versus 85; P < 005), or healthy children (75 versus 87; P < 005) Parents of children with constipation reported lower scores than did their children (61 versus 70; P < 005) Children with constipation had longer duration of symptoms than did the controls with inflammatory bowel disease and gastroesophageal reflux disease (438 months versus 142 months; P < 0001) Prolonged duration of symptoms fur children with constipation correlated with lower parent-reported scores (P < 0002) Conclusions: At initial evaluation, children with constipation have a lower quality of life than do children with inflammatory bowel disease or gastroesophageal reflux disease Self-reported lower scores may be a reflection of impaired physical ability Parental perceptions of low quality of life are probably impacted by the duration of their child's symptoms and by family members with similar complaints Practitioners should be aware of the high level of parental concern and the relatively low self-reported and parent-reported quality of life in children with chronic constipation as they plan therapy

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Journal Article

Childhood functional gastrointestinal disorders

Abstract: This is the first attempt at defining criteria for functional gastrointestinal disorders (FGIDs) in infancy, childhood, and adolescence. The decision-making process was as for adults and consisted of arriving at consensus, based on clinical experience. This paper is intended to be a quick reference. The classification system selected differs from the one used in the adult population in that it is organized according to main complaints instead of being organ-targeted. Because the child is still developing, some disorders such as toddler’s diarrhea (or functional diarrhea) are linked to certain physiologic stages; others may result from behavioral responses to sphincter function acquisition such as fecal retention; others will only be recognizable after the child is cognitively mature enough to report the symptoms (e.g., dyspepsia). Infant regurgitation, rumination, and cyclic vomiting constitute the vomiting disorders. Abdominal pain disorders are classified as: functional dyspepsia, irritable bowel syndrome (IBS), functional abdominal pain, abdominal migraine, and aerophagia. Disorders of defecation include: infant dyschezia, functional constipation, functional fecal retention, and functional non-retentive fecal soiling. Some disorders, such as IBS and dyspepsia and functional abdominal pain, are exact replications of the adult criteria because there are enough data to confirm that they represent specific and similar disorders in pediatrics. Other disorders not included in the pediatric classification, such as functional biliary disorders, do occur in children; however, existing data are insufficient to warrant including them at the present time. For these disorders, it is suggested that, for the time being, clinicians refer to the criteria established for the adult population.
Journal ArticleDOI

Epidemiology of constipation in children and adults: a systematic review.

TL;DR: The epidemiology of constipation in children was investigated in 19 articles and prevalence rate was between 0.7% and 29.6% (median 12%).
Journal ArticleDOI

Epidemiology of childhood constipation: a systematic review

TL;DR: A systematic review of the published literature found that childhood constipation is a common problem worldwide and large epidemiologic studies with the use of generally accepted diagnostic criteria are needed to define the precise prevalence of constipation.
Journal ArticleDOI

Systematic review: impact of constipation on quality of life in adults and children

TL;DR: In this article, a comprehensive literature search identified studies in constipation that used a generic QoL tool and compared with published results using the same tools in other chronic conditions, including chronic conditions such as allergies, musculoskeletal conditions and inflammatory bowel disease.
Journal ArticleDOI

Health Utilization and Cost Impact of Childhood Constipation in the United States

TL;DR: It is demonstrated that childhood constipation has a significant impact on the use and cost of medical care services, and the estimated cost per year is 3 times than that in children without constipation, which likely is an underestimate of the actual burden of Childhood constipation.
References
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Journal ArticleDOI

PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations.

TL;DR: The PedsQL distinguished between healthy children and pediatric patients with acute or chronic health conditions, was related to indicators of morbidity and illness burden, and displayed a factor-derived solution largely consistent with the a priori conceptually-derived scales.
Journal ArticleDOI

The PedsQL: measurement model for the pediatric quality of life inventory.

TL;DR: The results support the PedsQL as a reliable and valid measure of HRQOL and makes it flexible enough to be used in a variety of research and clinical applications for pediatric chronic health conditions.
Journal ArticleDOI

The PedsQL 4.0 as a pediatric population health measure: feasibility, reliability, and validity.

TL;DR: Measuring pediatric HRQOL may be a way to evaluate the health outcomes of SCHIP and demonstrate the feasibility, reliability, and validity of the PedsQL 4.0 as a pediatric population health outcome.
Journal ArticleDOI

Health-related quality of life of severely obese children and adolescents.

TL;DR: Severely obeseChildren and adolescents have lower health-related QOL than children and adolescents who are healthy and similar QOL as those diagnosed as having cancer.
Journal Article

Childhood functional gastrointestinal disorders

Abstract: This is the first attempt at defining criteria for functional gastrointestinal disorders (FGIDs) in infancy, childhood, and adolescence. The decision-making process was as for adults and consisted of arriving at consensus, based on clinical experience. This paper is intended to be a quick reference. The classification system selected differs from the one used in the adult population in that it is organized according to main complaints instead of being organ-targeted. Because the child is still developing, some disorders such as toddler’s diarrhea (or functional diarrhea) are linked to certain physiologic stages; others may result from behavioral responses to sphincter function acquisition such as fecal retention; others will only be recognizable after the child is cognitively mature enough to report the symptoms (e.g., dyspepsia). Infant regurgitation, rumination, and cyclic vomiting constitute the vomiting disorders. Abdominal pain disorders are classified as: functional dyspepsia, irritable bowel syndrome (IBS), functional abdominal pain, abdominal migraine, and aerophagia. Disorders of defecation include: infant dyschezia, functional constipation, functional fecal retention, and functional non-retentive fecal soiling. Some disorders, such as IBS and dyspepsia and functional abdominal pain, are exact replications of the adult criteria because there are enough data to confirm that they represent specific and similar disorders in pediatrics. Other disorders not included in the pediatric classification, such as functional biliary disorders, do occur in children; however, existing data are insufficient to warrant including them at the present time. For these disorders, it is suggested that, for the time being, clinicians refer to the criteria established for the adult population.
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