Circadian rhythm and cardiovascular disorders
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This work is distributed under the terms of the License http://creativecommons.org/licenses/by-nc/3.0/.Abstract:
License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php ChronoPhysiology and Therapy 2014:4 27–40 ChronoPhysiology and Therapy Dovepressread more
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Journal Article
Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo
TakeshigeKunieda,TohruMinamino,TaroKatsuno,KaoruTateno,Jun-ichiroNishi,HideyukiMiyauchi,MasayukiOrimo,ShoOkada,IsseiKomuro +8 more
TL;DR: It is reported here that cellular senescence impairs circadian rhythmicity both in vitro and in vivo.
Journal Article
Daily and Circadian Rhythms of Tissue Factor Pathway Inhibitor and Factor VII Activity
MirkoPinotti,CristianoBertolucci,FrancescoPortaluppi,IlariaColognesi,ElenaFrigato,AugustoFoà,FrancescoBernardi +6 more
TL;DR: Investigation of temporal fluctuations of tissue factor pathway inhibitor (TFPI) activity in constant darkness indicated the existence of daily rhythms for TFPI and of true circadian rhythms for FVII.
Journal ArticleDOI
Implications of Circadian Rhythm in Stroke Occurrence: Certainties and Possibilities.
TL;DR: In this paper, the authors summarize the literature data on the circadian variation of cerebrovascular events according to physiological, cellular, and molecular circadian changes, to survey the available information on the chronotherapy and chronoprophylaxis of stroke and its risk factors, as well as to discuss the less reviewed impact of the circadian rhythm in stroke onset on patient outcome and functional status after stroke.
Journal ArticleDOI
Circadian regulation of cardiac metabolism
TL;DR: In this paper, the authors describe current findings on rhythmic cardiac metabolism and discuss the intricate regulation of circadian rhythm and the consequences of rhythm disruption, which is critical in translating preclinical findings from nocturnal-animal models as well as in developing novel chronotherapeutic strategies.
References
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Endothelial Progenitor Cells: Characterization and Role in Vascular Biology
Carmen Urbich,Stefanie Dimmeler +1 more
TL;DR: This review summarizes the mechanisms regulating endothelial progenitor cell–mediated neovascularization and reendothelialization and describes the characterization of the different progenitors cell populations.
Journal ArticleDOI
Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
Fred W. Turek,Corinne E. Joshu,Corinne E. Joshu,Akira Kohsaka,Akira Kohsaka,Emily Lin,Emily Lin,Ganka Ivanova,Ganka Ivanova,Erin L. McDearmon,Erin L. McDearmon,Aaron D. Laposky,Sue Losee-Olson,Amy Easton,Dalan R. Jensen,Robert H. Eckel,Joseph S. Takahashi,Joseph S. Takahashi,Joseph Bass,Joseph Bass +19 more
TL;DR: Estimation of transcripts encoding selected hypothalamic peptides associated with energy balance was attenuated in the Clock mutant mice, suggesting that the circadian clock gene network plays an important role in mammalian energy balance.
Journal ArticleDOI
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
Francesca Damiola,Nguyet Le Minh,Nicolas Preitner,Benoît Kornmann,Fabienne Fleury-Olela,Ueli Schibler +5 more
TL;DR: It is shown that temporal feeding restriction under light-dark or dark-dark conditions can change the phase of circadian gene expression in peripheral cell types by up to 12 h while leaving thephase of cyclic gene expressionIn the SCN unaffected.
Journal ArticleDOI
Circadian variation in the frequency of onset of acute myocardial infarction
James E. Muller,Peter Stone,Zoltan G. Turi,John D. Rutherford,Charles A. Czeisler,Corette B. Parker,W. K. Poole,Eugene R. Passamani,Robert Roberts,Thomas L. Robertson +9 more
TL;DR: If coronary arteries become vulnerable to occlusion when the intima covering an atherosclerotic plaque is disrupted, the circadian timing of myocardial infarction may result from a variation in the tendency to thrombosis.
Journal ArticleDOI
Ambulatory blood pressure. An independent predictor of prognosis in essential hypertension.
Paolo Verdecchia,Carlo Porcellati,Giuseppe Schillaci,Claudia Borgioni,Antonella Ciucci,Massimo Battistelli,M Guerrieri,Camillo Gatteschi,Ivano Zampi,Antonella Santucci,Carla Santucci,Gianpaolo Reboldi +11 more
TL;DR: It is suggested that ambulatory blood pressures stratifies cardiovascular risk in essential hypertension independent of clinic blood pressure and other traditional risk markers including echocardiographic left ventricular hypertrophy.