Clinical manifestations, treatment and control of infections caused by Clostridium difficile
Reads0
Chats0
TLDR
Clostridium difficile should be suspected in patients who present with nosocomial diarrhoea and the administration of probiotics such as Saccharomyces boulardii, Lactobacillus sp.About:
This article is published in Clinical Microbiology and Infection.The article was published on 2005-01-01 and is currently open access. It has received 72 citations till now. The article focuses on the topics: Clostridium difficile & Vancomycin.read more
Citations
More filters
Journal ArticleDOI
Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
Stuart H. Cohen,Dale N. Gerding,Stuart Johnson,Ciaran P. Kelly,Vivian G. Loo,L. Clifford McDonald,Jacques Pépin,Mark H. Wilcox +7 more
TL;DR: This guideline updates recommendations regarding epidemiology, diagnosis, treatment, and infection control and environmental management of Clostridium difficile.
Journal ArticleDOI
European evidence-based Consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease.
Jean-François Rahier,Fernando Magro,Candida Abreu,Alessandro Armuzzi,Shomron Ben-Horin,Yehuda Chowers,Mario Cottone,L. de Ridder,Glen A. Doherty,Robert Ehehalt,Maria Esteve,K.H. Katsanos,Charlie W. Lees,Eithne MacMahon,Tom G. Moreels,Walter Reinisch,Herbert Tilg,Lydjie Tremblay,Gigi Veereman-Wauters,N. Viget,Yazdan Yazdanpanah,Rami Eliakim,Jean-Frederic Colombel +22 more
TL;DR: The treatment of inflammatory bowel disease has been revolutionised over the past decade by the increasing use of immunomodulators, mainly azathioprine/6-mercaptopurine and methotrexate, together with the advent of biological therapy.
Journal ArticleDOI
Proton pump inhibitor use and risk of community-acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy
TL;DR: Exposure to a proton pump inhibitor in the 90 days before the index date was associated with an increased risk of community-acquired CDAD and certain comorbidities, in particular renal failure, inflammatory bowel disease and malignant disease, as well as prior methicillin-resistant Staphylococcus aureus infection, were also associated with a increased risk.
Journal ArticleDOI
Consequences of Clostridium difficile infection: understanding the healthcare burden
Emilio Bouza,Emilio Bouza +1 more
TL;DR: Infection with C. difficile imposes a significant burden not only on patients, owing to increased morbidity and mortality, but also on healthcare systems and society in general, and measures to more effectively prevent CDI and reduce CDI recurrence rates may help to reduce this burden.
Journal ArticleDOI
Yield of Stool Culture with Isolate Toxin Testing versus a Two-Step Algorithm Including Stool Toxin Testing for Detection of Toxigenic Clostridium difficile
Megan E. Reller,Clara Lema,Trish M. Perl,Mian Cai,Tracy L. Ross,Kathleen Speck,Karen C. Carroll +6 more
TL;DR: The incremental yield of stool culture versus two-step algorithm for optimal detection of toxigenic Clostridium difficile is examined and it is concluded that GDH is an excellent screening test and that culture with isolate CCNA testing detects an additional 23% of toxigeic C. difficiles missed by direct CCNA.
References
More filters
Journal ArticleDOI
Nosocomial acquisition of Clostridium difficile infection
TL;DR: Nosocomial C. difficile infection, which was associated with diarrhea in about one third of cases, is frequently transmitted among hospitalized patients and that the organism is often present on the hands of hospital personnel caring for such patients.
Journal ArticleDOI
Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia.
TL;DR: Results suggest that toxin-producing clostridia are responsible for antibiotic-associated pseudomembranous colitis.
Journal ArticleDOI
Clinical practice. Antibiotic-associated diarrhea.
TL;DR: This discussion covers antibiotic agents that have been associated with some effect and the more common mechanisms of drug induced bowel injury are listed below.
Journal ArticleDOI
Practice Guidelines for the Management of Infectious Diarrhea
Richard L. Guerrant,Thomas Van Gilder,Theodore S. Steiner,Nathan M. Thielman,Laurence Slutsker,Robert V. Tauxe,Thomas W. Hennessy,Patricia M. Griffin,Herbert L. DuPont,R. Bradley Sack,Phillip I. Tarr,Marguerite A. Neill,Irving Nachamkin,L. Barth Reller,Michael T. Osterholm,Michael L. Bennish,Larry K. Pickering +16 more
TL;DR: Prevention by avoidance of undercooked meat or seafood, avoidance of unpasteurized milk or soft cheese, and selected use of available typhoid vaccines for travelers to areas where typhoid is endemic are key to the control of infectious diarrhea.
Journal ArticleDOI
Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile.
TL;DR: A conservative estimate of the cost of this disease in the United States exceeds $1.1 billion per year after adjustment for age, comorbidity, and disease severity.