Open Access
Comparative studies of anticancer and antimicrobial potential of bioinspired silver and silver-selenium nanoparticles
Amit Kumar Mittal,Kaushik Thanki,Sanyog Jain,Uttam Chand Banerjee +3 more
- Vol. 3, Iss: 2, pp 22-27
TLDR
The results concluded that Syzygium cumini silver nanoparticles were highly active at the minimum concentration of 10 µg/mL against all type of cells and destroy the bacterial and tumour cells in a dose-dependent manner.Abstract:
The antimicrobial and anticancer potential of synthesized silver nanoparticles by various medicinal plants and silver-selenium nanoparticles by phytochemicals (quercetin and gallic acid) are reported here. Medicinal plants such as Syzygium cumini , Azadirachta indica and Catharanthusroseus and quercetin-gallic acid as phytochemicals were selected after screening of various plants and phytochemicals in terms of the ability of nanoparticle synthesis. The synthesized nanoparticles were characterized using various analytical instrumentation techniques. All the nanoparticles are having less than 40 nm in size as confirmed by electron microscopy. Bactericidal action of the nanoparticles was determined using broth microdilution method on two microbial strains ( Escherichia coli and Bacillus subtilis) . The results specified that all types of nanoparticles exhibited comparable bactericidal action against the different strains at 100 µg/ml, when compared to the standard drug, chloramphenicol (50 µg/ml). Additionally, the anticancer potential of the nanoparticles was evaluated using MTT assay on various cancer cells (HeLa, Hek-293 and MCF-7). The results concluded that Syzygium cumini silver nanoparticles were highly active at the minimum concentration of 10 µg/mL against all type of cells. The synthesized nanoparticles destroy the bacterial and tumour cells in a dose-dependent manner.read more
Citations
More filters
Journal ArticleDOI
Inorganic and metal nanoparticles and their antimicrobial activity in food packaging applications
TL;DR: This review has evaluated recent studies plus the applications of inorganic and metal nanoparticles mostly in food packaging applications along with their antimicrobial properties and reaction mechanisms.
Journal ArticleDOI
Green Chemistry Synthesis of Silver Nanoparticles and Their Potential Anticancer Effects.
Zubair Ahmed Ratan,Zubair Ahmed Ratan,Mohammad Faisal Haidere,Nurunnabi,Sadi Md. Shahriar,A. J. Saleh Ahammad,Youn Young Shim,Youn Young Shim,Youn Young Shim,Martin J. T. Reaney,Martin J. T. Reaney,Jae Youl Cho +11 more
TL;DR: This review summarized the recent progress and achievements in biogenic AgNPs synthesis and their potential uses as anticancer agents.
Journal ArticleDOI
Selenium nanoparticles synthesized using an eco-friendly method: dye decolorization from aqueous solutions, cell viability, antioxidant, and antibacterial effectiveness
Badreah A. Al Jahdaly,Najlaa S. Al-Radadi,Ghada M.G. Eldin,Albandary Almahri,M.K. Ahmed,Kamel R. Shoueir,Kamel R. Shoueir,Izabela Janowska +7 more
TL;DR: Selenium nanoparticles fabricated using a green microwave technique in the presence of ascorbic acid indicate that manipulating multifunctional nanoparticles for versatile wound and skin treatment applications is highly encouraging.
Journal ArticleDOI
A Systematic Review of Biosynthesized Metallic Nanoparticles as a Promising Anti-Cancer-Strategy.
Anisa Andleeb,Aneeta Andleeb,Salman Asghar,Gouhar Zaman,Muhammad Tariq,Azra Mehmood,Muhammad Nadeem,Christophe Hano,José M. Lorenzo,Bilal Haider Abbasi +9 more
TL;DR: In this article, the authors summarized the recent advancements in the biosynthesis of Ag, Au, Zn and Cu NPs with emphasis on their mechanism of action and highlighted the future prospects and opportunities of nano-therapeutics.
Journal ArticleDOI
Biogenic synthesis of silver nanoparticles: Antibacterial and cytotoxic potential.
TL;DR: The current investigation suggested that the green production of AgNPs could be a suitable substitute to large-scale production ofAgNPs, since stable and active nanoparticles could be obtained.
References
More filters
Journal ArticleDOI
The bactericidal effect of silver nanoparticles
Jose Ruben Morones,Jose Luis Elechiguerra,A. Camacho,Katherine B. Holt,Juan B. Kouri,Jose Tapia Ramirez,Miguel Jose Yacaman +6 more
TL;DR: The results indicate that the bactericidal properties of the nanoparticles are size dependent, since the only nanoparticles that present a direct interaction with the bacteria preferentially have a diameter of approximately 1-10 nm.
Journal ArticleDOI
Silver nanoparticles as a new generation of antimicrobials.
TL;DR: Silver nanoparticles have emerged up with diverse medical applications ranging from silver based dressings, silver coated medicinal devices, such as nanogels, nanolotions, etc, due to its capability of modulating metals into their nanosize.
Journal ArticleDOI
Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the Gram-negative bacterium Escherichia coli.
TL;DR: This is the first comparative study on the bactericidal properties of silver nanoparticles of different shapes, and the results demonstrate thatsilver nanoparticles undergo a shape-dependent interaction with the gram-negative organism E. coli.
Journal ArticleDOI
Green synthesis of metal nanoparticles using plants
TL;DR: Most of the plants used in metal nanoparticle synthesis are shown in this article, and the advantages of using plant and plant-derived materials for biosynthesis of metal nanoparticles have interested researchers to investigate mechanisms of metal ions uptake and bioreduction by plants, and to understand the possible mechanism of nanoparticle formation in plants.
Journal ArticleDOI
Applications of nanoparticles in biology and medicine
TL;DR: This brief review tries to summarise the most recent developments in the field of applied nanomaterials, in particular their application in biology and medicine, and discusses their commercialisation prospects.