Journal ArticleDOI
Comparing speech characteristics in spinocerebellar ataxias type 3 and type 6 with Friedreich ataxia.
Bettina Brendel,Matthis Synofzik,Hermann Ackermann,Tobias Lindig,Theresa Schölderle,Ludger Schöls,Wolfram Ziegler +6 more
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TLDR
Comparisons of dysarthria profiles of patients with SCA3 and SCA6 vs. Friedreich ataxia (FRDA) showed regularity of DDK was specifically impaired inSCA3, whereas impairments of speech parameters, i.e., rate and modulation were stronger affected in SCA 6.Abstract:
Patterns of dysarthria in spinocerebellar ataxias (SCAs) and their discriminative features still remain elusive. Here we aimed to compare dysarthria profiles of patients with (SCA3 and SCA6 vs. Friedreich ataxia (FRDA), focussing on three particularly vulnerable speech parameters (speaking rate, prosodic modulation, and intelligibility) in ataxic dysarthria as well as on a specific oral non-speech variable of ataxic impairment, i.e., the irregularity of oral motor diadochokinesis (DDK). 30 Patients with SCA3, SCA6, and FRDA, matched for group size (n = 10 each), disease severity, and disease duration produced various speech samples and DDK tasks. A discriminant analysis was used to differentiate speech and non-speech parameters between groups. Regularity of DDK was specifically impaired in SCA3, whereas impairments of speech parameters, i.e., rate and modulation were stronger affected in SCA6. Speech parameters are particularly vulnerable in SCA6, while non-speech oral motor features are notably impaired in SCA3.read more
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Journal ArticleDOI
Consensus Paper: Neurophysiological Assessments of Ataxias in Daily Practice
Winfried Ilg,Meret Branscheidt,Ankur Butala,Pablo Celnik,L. de Paola,Fay B. Horak,Ludger Schöls,H.A.G. Teive,Adam P. Vogel,Adam P. Vogel,David S. Zee,Dagmar Timmann +11 more
TL;DR: The purpose of this consensus paper is to review electrophysiological abnormalities and to provide a guideline of neurophysiological assessments in cerebellar ataxias and agree that quantitative measures of ataxia are desirable as biomarkers.
Journal ArticleDOI
Gauging the Auditory Dimensions of Dysarthric Impairment: Reliability and Construct Validity of the Bogenhausen Dysarthria Scales (BoDyS).
TL;DR: The 9 auditory scales of the Bogenhausen Dysarthria Scales provide a reliable and valid profile of dysarthric impairment and permit standardized measurement of clinically relevant dimensions of Dysarthric speech.
Journal ArticleDOI
Redefining cerebellar ataxia in degenerative ataxias: lessons from recent research on cerebellar systems
TL;DR: Considering the neurophysiological properties of the cerebellary system, degenerative ataxias are classified into four types depending on which system is involved: Purkinje cells, the corticopontocerebellar system, the spinocere Bellar system and the cere Bellar deep nuclei.
Journal ArticleDOI
Reference values of maximum performance tests of speech production.
S. Knuijt,Johanna G. Kalf,Baziel G.M. van Engelen,Alexander C. H. Geurts,Bert J. M. de Swart +4 more
TL;DR: Reference values of four maximum performance tests are presented for comparing the performance of dysarthric patients with non-pathological performance, with age identified as most important factor influencing maximum speech performance.
Journal ArticleDOI
Automated Topographic Prominence based quantitative assessment of speech timing in Cerebellar Ataxia
Bipasha Kashyap,Malcolm K. Horne,Pubudu N. Pathirana,Laura Power,David J. Szmulewicz,David J. Szmulewicz,David J. Szmulewicz +6 more
TL;DR: An automated objective method based on a single syllable repetition task to detect and quantify speech-timing anomalies in ataxic speech is presented and suitability of this scheme to monitor speech motor abnormalities in persons suffering from CA is supported.
References
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Journal ArticleDOI
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Journal ArticleDOI
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Journal ArticleDOI
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Related Papers (5)
Perceptual and acoustic analysis of speech in individuals with spinocerebellar ataxia (SCA).
Speech Rate and Rhythm in Cerebellar Dysarthria: An Acoustic Analysis of Syllabic Timing
Hermann Ackermann,Ingo Hertrich +1 more
Scale for the assessment and rating of ataxia: development of a new clinical scale.
T. Schmitz-Hübsch,S. Tezenas du Montcel,Laszlo Baliko,José Berciano,S Boesch,Chantal Depondt,Paola Giunti,C. Globas,Jon Infante,J-S Kang,Berry Kremer,Christian Mariotti,Béla Melegh,Massimo Pandolfo,Maryla Rakowicz,P Ribai,Rafał Rola,Ludger Schöls,Sandra Szymanski,B.P.C. van de Warrenburg,Alexandra Durr,Thomas Klockgether,Roberto Fancellu +22 more