Journal ArticleDOI
Competitive binding of phenylbutazone and colchicine to serum albumin in multidrug therapy: A spectroscopic study
Anna Sułkowska,M. Maciążek-Jurczyk,Barbara Bojko,J. Równicka,I. Zubik-Skupień,E. Temba,Danuta Pentak,Wiesław W. Sułkowski +7 more
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TLDR
It was concluded that colchicine may probably cause displacement of phenylbutazone from its complex with serum albumin (SA) and Static and dynamic quenching for the binary and ternary systems showed that phenyl butazone does not affect the complex formed between colchichine and BSA, and colchicaine has no effect on the Phe–BSA complex.About:
This article is published in Journal of Molecular Structure.The article was published on 2008-06-18. It has received 130 citations till now. The article focuses on the topics: Serum albumin & Human serum albumin.read more
Citations
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Journal ArticleDOI
Bovine and human serum albumin interactions with 3-carboxyphenoxathiin studied by fluorescence and circular dichroism spectroscopy.
Aurica Varlan,Mihaela Hillebrand +1 more
TL;DR: The interactions of 3-carboxyphenoxathiin with BSA and HSA have been studied by fluorescence and circular dichroism spectroscopy, revealing a 1:1 interaction with a binding constant of about 105 M-1.
Journal ArticleDOI
Biological evaluation of a novel water soluble sulphur bridged binuclear copper(II) thiosemicarbazone complex.
TL;DR: Investigations of antioxidative properties showed that the copper(II) nitrate complex has strong radical scavenging properties and the cytotoxic effect of the complex was examined on HeLa, Hep G2, and HEp-2, which showing that the complex exhibited substantial cytotoxicity specificity on He La over the other two.
Journal ArticleDOI
Studies on the interaction between imidacloprid and human serum albumin: spectroscopic approach.
TL;DR: The experimental results showed that the fluorescence quenching of HSA by IMI was a result of the formation of IMI-HSA complex; staticQuenching was confirmed to result in the fluorescent quenched.
Journal ArticleDOI
Synthesis of novel heterobimetallic copper(I) hydrazone Schiff base complexes: A comparative study on the effect of heterocyclic hydrazides towards interaction with DNA/protein, free radical scavenging and cytotoxicity
Palanisamy Sathyadevi,Paramasivam Krishnamoorthy,Rachel R. Butorac,Alan H. Cowley,N. Dharmaraj +4 more
TL;DR: Two new copper(I) hydrazone complexes have been synthesised from bivalent copper precursor [CuCl(2)(PPh(3))(2)] and ferrocene containing bidentate hydraz one ligands HL(1) or HL(2) (2) based on the elemental analyses and spectroscopic data.
Journal ArticleDOI
Probing the binding of lomefloxacin to a calf thymus DNA-histone H1 complex by multi-spectroscopic and molecular modeling techniques
TL;DR: In this article, the interaction between lomefloxacin (LMF) and a ctDNA-H1 complex was investigated by various spectroscopies, as well as viscometry and molecular modeling techniques.
References
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BookDOI
Molecular fluorescence : principles and applications
TL;DR: In this article, the effects of intermolecular photophysical processes on fluorescence emission are discussed and an analysis of the effect of polarity of fluorescence emissions is presented.
Book ChapterDOI
Structure of serum albumin.
Daniel C. Carter,Joseph X. Ho +1 more
TL;DR: This chapter provides an insight of the findings of past significant papers with the current knowledge of the recently determined high resolution X-ray structure of serum albumin and suggests that AFP may have a higher affinity for some unknown ligands important for fetal development.
Book
All About Albumin: Biochemistry, Genetics, and Medical Applications
TL;DR: The Albumin Molecule: Its Structure and Chemical Properties and Practical Aspects: Albumin in the Laboratory.
Journal ArticleDOI
Fluorescence quenching studies with proteins.
TL;DR: A review of the use of the technique of solute fluorescence quenching to study the structure and dynamics of proteins and a number of factors are discussed that must be considered in analyzing such data.
Journal Article
The characterization of two specific drug binding sites on human serum albumin.
TL;DR: The binding of a number of fluorescent probe molecules to human serum albumin has been studied and changes in probe fluorescence were shown to be a result of competitive displacement by drugs.