Journal ArticleDOI
Complexing of serum pre-β- and β-lipoproteins and acid mucopolysaccharides☆
TLDR
In this article, pre-β- and β-lipoproteins were observed to form insoluble complexes with sulfated acid mucopolysaccharides (MPS) in presence of Cat+, and the optimum conditions for the formation of the complexes were investigated with varying amounts of MPS and Ca 2+.About:
This article is published in Atherosclerosis.The article was published on 1970-11-01. It has received 143 citations till now.read more
Citations
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Journal ArticleDOI
Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.
Russell Ross,John A. Glomset +1 more
Journal ArticleDOI
The Interaction between Human Plasma Lipoproteins and Connective Tissue Glycosaminoglycans
TL;DR: Equilibration of the same lipoproteins with glycosaminoglycan-substituted agarose gels at pH 7.4 showed that VLDL as well as LDL were bound to gels containing heparin, dermatan sulfate, heparan sulfates, and chondroitin 4-sulfate, provided the ionic strength was sufficiently low.
Book ChapterDOI
Structure and biological activity of heparin
TL;DR: The structure and biological activity of heparin are described, being an alternating copolymer of a hexosamine and an alduronic acid, and the repeating disaccharide units constituting the largest fraction of the most common GAG are elaborated in the chapter.
Journal ArticleDOI
Proteoglycans in Atherosclerosis and Restenosis: Key Roles for Versican
TL;DR: The critical importance of this specific ECM component in atherosclerosis and restenosis is highlighted, which influences the assembly of ECM and controls elastic fiber fibrillogenesis, which is of fundamental importance in ECM remodeling during vascular disease.
Book ChapterDOI
The relationship between plasma and tissue lipids in human atherosclerosis.
TL;DR: This chapter discusses the relationship between plasma and tissue lipids in human atherosclerosis with a marked increase in the proportion of free cholesterol, decrease in proportion of ester cholesterol, and change in the cholesterol ester fatty acid pattern in normal intima.
References
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Journal ArticleDOI
Fat Transport in Lipoproteins — An Integrated Approach to Mechanisms and Disorders
TL;DR: The Type II hyperlipoproteinemia as mentioned in this paper is defined as an increase in the concentration of lipoproteins that have discrete β-mobility, and is defined by the Type II lipoprotein pattern.
Journal ArticleDOI
Electrophoretic separation of plasma lipoproteins in agarose gel
TL;DR: The clearcut separation of lipoproteins by this method will facilitate the classification of hyperlipoproteinemias and improve quantitative estimates oflipoprotein distribution.