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Journal ArticleDOI

Compounds from Syzygium aromaticum possessing growth inhibitory activity against oral pathogens

Lining Cai, +1 more
- 22 Oct 1996 - 
- Vol. 59, Iss: 10, pp 987-990
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TLDR
A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia.
Abstract
A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia. By means of bioassay-directed chromatographic fractionation, eight active compounds were isolated from this extract and were identified as 5,7-dihydroxy-2-methylchromone 8-C-beta-D-glucopyranoside, biflorin, kaempferol, rhamnocitrin, myricetin, gallic acid, ellagic acid, and oleanolic acid, based on spectroscopic evidence. The antibacterial activity of these pure compounds was determined against Streptococcus mutans, Actinomyces viscosus, P. gingivalis, and P. intermedia. The flavones, kaempferol and myricetin, demonstrated potent growth-inhibitory activity against the periodontal pathogens P. gingivalis and P. intermedia.

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Effects of Baking and Frying on the Fumonisin B1 Content of Corn-Based Foods

TL;DR: In this article, the effects of cooking and frying on the stability of fumonisin B1 (FB1) spiked into corn-based foods were investigated and it was found that FB1 began to degrade at frying temperatures ≥ 180 °C and times ≥ 8 min.
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Quinoa Secondary Metabolites and Their Biological Activities or Functions.

TL;DR: This review focuses on the knowledge of the structures, biological activities and functions of quinoa secondary metabolites, which include phenolic acids, flavonoids, terpenoids, steroids, and nitrogen-containing compounds.
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Abhisin: a potential antimicrobial peptide derived from histone H2A of disk abalone (Haliotis discus discus).

TL;DR: The results suggest that abhisin is a potential antimicrobial agent, and its precursor histone H2A may be involved in the innate immune defense system in abalone.
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Phytochemical evaluation and pharmacological activity of syzygium aromaticum: a comprehensive review

TL;DR: This review presents an overview and details of the phytochemical and pharmacological investigations on the S. aromaticum, one of the most important herbs in traditional medicine, having a wide spectrum of biological activity.
References
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Journal ArticleDOI

Chemotherapeutic agents for controlling plaque and gingivitis

TL;DR: A new generation of more specific antibacterial agents that interfere with attachment to pellicle can be developed, it is hard to predict, however, that they will affect gingivitis, at least until there is more information on what specific organisms should be targeted.
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Effect of tea polyphenols on glucan synthesis by glucosyltransferase from Streptococcus mutans

TL;DR: Extracts of green tea and black tea, and polyphenol mixtures showed appreciable inhibition in the synthesis of insoluble glucan, and theaflavin and its mono- and digallates had potent inhibitory activities at concentrations of 1-10 mM against GTF.
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Studies on Scutellariae radix. Part II: The antibacterial substance.

TL;DR: Ether extract of this crude drug showed a relatively marked antibacterial activity against Gram-positive bacteria and the structure of one of these was elucidated as 2( S), 2′, 5, 6′, 7-tetrahydroxyflavanone.
Journal ArticleDOI

Antimicrobial agents from higher plants. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. typica.

TL;DR: Bioassay-directed fractionation of Glycyrrhiza glabra L. var.
Journal ArticleDOI

Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria.

TL;DR: The methanolic extract of Swartzia polyphylla DC had antibacterial activity against cariogenic bacteria, the mutans Streptococci, and this effect was not detected on isoflavone derivatives.
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