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Journal ArticleDOI

Compounds from Syzygium aromaticum possessing growth inhibitory activity against oral pathogens

Lining Cai, +1 more
- 22 Oct 1996 - 
- Vol. 59, Iss: 10, pp 987-990
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TLDR
A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia.
Abstract
A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia. By means of bioassay-directed chromatographic fractionation, eight active compounds were isolated from this extract and were identified as 5,7-dihydroxy-2-methylchromone 8-C-beta-D-glucopyranoside, biflorin, kaempferol, rhamnocitrin, myricetin, gallic acid, ellagic acid, and oleanolic acid, based on spectroscopic evidence. The antibacterial activity of these pure compounds was determined against Streptococcus mutans, Actinomyces viscosus, P. gingivalis, and P. intermedia. The flavones, kaempferol and myricetin, demonstrated potent growth-inhibitory activity against the periodontal pathogens P. gingivalis and P. intermedia.

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Medicinal Plant Images

TL;DR: As high antioxidant levels have previously been demonstrated to act as preventative effects against the development of degenerative chronic diseases such as cancer, cardiovascular diseases, neural degeneration, diabeties and obesity, it has been postulated that Kakadu plum fruit may also be an effective preventative against these diseases.
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Syzygium aromaticum (L.) Merr. & Perry (Myrtaceae): Giroflier

TL;DR: La fleur, hermaphrodite, possède de nombreuses étamines (formant un pompon) and un pistil à ovaire infère à deux loges, est une drupe ellipsoı̈de brun violacée, contenant une seule graine d’environ 1,5 cm de long.
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1α,2α-Epoxy-3β-hydroxy oleanolic acid derivatives regulation of the metabolism, haemolysis and β-lactamase gene expression in vitro and their structure-microbicidal activity relationship.

TL;DR: Modifications in the synthetic compounds, such as the introduction of an ortho-cyano-substituted benzyl group and a short chain alkyl ester at the 28-carboxyl, could enhance antibacterial activity and provide basic evidence for the optimization of 1α,2α-epoxy-3β-hydroxyl oleanolic acid derivatives.
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Acute phase protein mRNA expressions and enhancement of antioxidant defense system in Black-meated Silkie Fowls supplemented with clove ( Eugenia caryophyllus) extracts under the influence of chronic heat stress

TL;DR: Clove extracts supplementation decreased oxidative stress in the heat-stressed black-meated fowls by alleviating negative effects of heat stress via improvement in growth performance, antioxidant defense mechanisms, immunity, and regulate the expression of acute phase genes in the liver and immunological organs.
References
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Journal ArticleDOI

Chemotherapeutic agents for controlling plaque and gingivitis

TL;DR: A new generation of more specific antibacterial agents that interfere with attachment to pellicle can be developed, it is hard to predict, however, that they will affect gingivitis, at least until there is more information on what specific organisms should be targeted.
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Effect of tea polyphenols on glucan synthesis by glucosyltransferase from Streptococcus mutans

TL;DR: Extracts of green tea and black tea, and polyphenol mixtures showed appreciable inhibition in the synthesis of insoluble glucan, and theaflavin and its mono- and digallates had potent inhibitory activities at concentrations of 1-10 mM against GTF.
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Studies on Scutellariae radix. Part II: The antibacterial substance.

TL;DR: Ether extract of this crude drug showed a relatively marked antibacterial activity against Gram-positive bacteria and the structure of one of these was elucidated as 2( S), 2′, 5, 6′, 7-tetrahydroxyflavanone.
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Antimicrobial agents from higher plants. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. typica.

TL;DR: Bioassay-directed fractionation of Glycyrrhiza glabra L. var.
Journal ArticleDOI

Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria.

TL;DR: The methanolic extract of Swartzia polyphylla DC had antibacterial activity against cariogenic bacteria, the mutans Streptococci, and this effect was not detected on isoflavone derivatives.
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