Journal ArticleDOI
Compounds from Syzygium aromaticum possessing growth inhibitory activity against oral pathogens
Lining Cai,Christine D. Wu +1 more
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A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia.Abstract:
A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia. By means of bioassay-directed chromatographic fractionation, eight active compounds were isolated from this extract and were identified as 5,7-dihydroxy-2-methylchromone 8-C-beta-D-glucopyranoside, biflorin, kaempferol, rhamnocitrin, myricetin, gallic acid, ellagic acid, and oleanolic acid, based on spectroscopic evidence. The antibacterial activity of these pure compounds was determined against Streptococcus mutans, Actinomyces viscosus, P. gingivalis, and P. intermedia. The flavones, kaempferol and myricetin, demonstrated potent growth-inhibitory activity against the periodontal pathogens P. gingivalis and P. intermedia.read more
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Ethnobotany of medicinal plants used in Antakya: A multicultural district in Hatay Province of Turkey.
TL;DR: This study compiled rich ethnomedicinal information that reflects the cosmopolitan structure of Antakya in a very good way and strongly suggests the importance of ethnobotanical studies in the development of new medicines.
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Propolis antimicrobial activity against periodontopathic bacteria
TL;DR: The positive results suggest that the propolis extract should be further tested as an adjuvant to periodontal therapy.
Journal ArticleDOI
Ethnobotanical survey and antibacterial activity of plants used in the Altiplane region of Mexico for the treatment of oral cavity infections.
Yazmín Rosas-Piñón,Alicia Mejía,Gloria Díaz-Ruiz,María Isabel Aguilar,Sobeida Sánchez-Nieto,J. Fausto Rivero-Cruz +5 more
TL;DR: It is demonstrated that most of the medicinal plants showed an antibacterial effect in vitro, and justified at least in part their use in traditional medicine.
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Antimicrobial compounds from Ceanothus americanus against oral pathogens
TL;DR: During the search for antimicrobial compounds from higher plant sources, a methanol extract of Ceanothus americanus demonstrated antimicrobial activity against selected oral pathogens.
References
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Journal ArticleDOI
Chemotherapeutic agents for controlling plaque and gingivitis
TL;DR: A new generation of more specific antibacterial agents that interfere with attachment to pellicle can be developed, it is hard to predict, however, that they will affect gingivitis, at least until there is more information on what specific organisms should be targeted.
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Effect of tea polyphenols on glucan synthesis by glucosyltransferase from Streptococcus mutans
TL;DR: Extracts of green tea and black tea, and polyphenol mixtures showed appreciable inhibition in the synthesis of insoluble glucan, and theaflavin and its mono- and digallates had potent inhibitory activities at concentrations of 1-10 mM against GTF.
Journal ArticleDOI
Studies on Scutellariae radix. Part II: The antibacterial substance.
TL;DR: Ether extract of this crude drug showed a relatively marked antibacterial activity against Gram-positive bacteria and the structure of one of these was elucidated as 2( S), 2′, 5, 6′, 7-tetrahydroxyflavanone.
Journal ArticleDOI
Antimicrobial agents from higher plants. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. typica.
TL;DR: Bioassay-directed fractionation of Glycyrrhiza glabra L. var.
Journal ArticleDOI
Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria.
TL;DR: The methanolic extract of Swartzia polyphylla DC had antibacterial activity against cariogenic bacteria, the mutans Streptococci, and this effect was not detected on isoflavone derivatives.
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