Journal ArticleDOI
Compounds from Syzygium aromaticum possessing growth inhibitory activity against oral pathogens
Lining Cai,Christine D. Wu +1 more
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A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia.Abstract:
A crude MeOH extract of Syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against Gram-negative anaerobic periodontal oral pathogens, including Porphyromonas gingivalis and Prevotella intermedia. By means of bioassay-directed chromatographic fractionation, eight active compounds were isolated from this extract and were identified as 5,7-dihydroxy-2-methylchromone 8-C-beta-D-glucopyranoside, biflorin, kaempferol, rhamnocitrin, myricetin, gallic acid, ellagic acid, and oleanolic acid, based on spectroscopic evidence. The antibacterial activity of these pure compounds was determined against Streptococcus mutans, Actinomyces viscosus, P. gingivalis, and P. intermedia. The flavones, kaempferol and myricetin, demonstrated potent growth-inhibitory activity against the periodontal pathogens P. gingivalis and P. intermedia.read more
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Journal ArticleDOI
Antibacterial activity of Tribulus terrestris and its synergistic effect with Capsella bursa-pastoris and Glycyrrhiza glabra against oral pathogens: an in-vitro study
Saman Soleimanpour,Fereshteh Sadat Sedighinia,Akbar Safipour Afshar,Reza Zarif,Kiarash Ghazvini +4 more
TL;DR: This in-vitro study provided scientific evidence to support uses of T. terrestris and its mixture with C. bursa-pastoris and G. glabra for the treatment of oral infections.
Journal ArticleDOI
Clinical efficacy of a herbal dentifrice on dentinal hypersensitivity: a randomized controlled clinical trial.
TL;DR: The novel herbal dentifrice can be recommended for treatment of dentinal hypersensitivity and was found to be significantly better compared to the placebo group at the end of 6 and 12 weeks in reduction of dentinals hypersensitivity.
Journal ArticleDOI
Evaluation of the Efficacy Of 0.2% Chlorhexidine versus Herbal Oral Rinse on Plaque Induced Gingivitis- A Randomized Clinical Trail
TL;DR: Herbal mouthwash was not associated with any discoloration of teeth or unpleasant taste and was effective in reducing plaque accumulation and gingival inflammation and Chlorhexidine still remains a gold standard in reduced plaque, gingivitis and bleeding on probing.
Journal ArticleDOI
Anticariogenic potentials of clove, tobacco and bitter kola.
TL;DR: Clove extract will be henceforth considered as a potential ingredient in toothpaste preparation after it was found that the n-hexane extract of clove seeds demonstrated preferential growth-inhibitory activity against the causal cariogenic pathogens (S. mutans) in dental caries.
Book ChapterDOI
The Potential of Plants of the Genus Syzygium (Myrtaceae) for the Prevention and Treatment of Arthritic and Autoimmune Diseases
TL;DR: A single extract may inhibit a microbial initiator of the disease, block the interaction between the antigen and the immune system, modulate the immune response if it is initiated, and inhibit the later phase inflammatory events, thereby lessening the symptoms.
References
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Journal ArticleDOI
Chemotherapeutic agents for controlling plaque and gingivitis
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Journal ArticleDOI
Effect of tea polyphenols on glucan synthesis by glucosyltransferase from Streptococcus mutans
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Journal ArticleDOI
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Journal ArticleDOI
Antimicrobial agents from higher plants. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. typica.
TL;DR: Bioassay-directed fractionation of Glycyrrhiza glabra L. var.
Journal ArticleDOI
Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria.
TL;DR: The methanolic extract of Swartzia polyphylla DC had antibacterial activity against cariogenic bacteria, the mutans Streptococci, and this effect was not detected on isoflavone derivatives.
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